Nathan Carl F相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Diaryl-Aminoindazole with Extensive In Vitro Mycobactericidal Activity Dependent on Exposure to Reactive Nitrogen Species

二芳基氨基吲唑具有广泛的体外杀分枝杆菌活性，该活性依赖于活性氮物种的暴露

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.5c00879

Warrier, Thulasi; Martínez-Hoyos, María; Porras De Francisco, Esther; Lenaerts, Anne J; Gruppo, Veronica; Robertson, Gregory T; Li, Kelin; Aubé, Jeffrey; Bonnet, Isabelle; Jiang, Xiuju; Dartois, Véronique; Prideaux, Brendan; Mundhra, Shashirekha; Nathan, Carl F; Mendoza-Losana, Alfonso

发表日期：2026

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The immunoproteasome regulates ILC2 responses by modulating mitochondrial capacity

免疫蛋白酶体通过调节线粒体功能来调控ILC2反应。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2518190122

Laurent, Paôline; Chaudhary, Vidyanath; Li, Daqiang; Ah Kioon, Marie Dominique; Zhang, Chen; Miller, William H; Liao, Hua; Lin, Gang; Nathan, Carl F; Barrat, Franck J

免疫/内分泌

发表日期：2025

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Thioquinazolinones as Antituberculosis Agents Targeting Phosphopantetheinyl Transferase

硫代喹唑啉酮类化合物作为靶向磷酸泛酰巯基转移酶的抗结核药物

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.5c00856

Singh, Amrita; Zwerneman, Logan T; Planck, Kyle; Kaneko, Takushi; Perkowski, Andrew J; Suh, Christine M; Alex, Alexander; Bean, James; Burns-Huang, Kristin; Zhang, David; Boshoff, Helena I M; Roubert, Christine; Krieger, Inna; Gardner, Mark; Cautain, Bastien; Cooper, Christopher B; Tanvir, Zaid; Sacchettini, James; Gold, Ben S; Rhee, Kyu Y; Fotouhi, Nader; Nathan, Carl F; Aubé, Jeffrey

发表日期：2025

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Mycobacterium tuberculosis, Mycobacterium kansasii and Rhodococcus equi induce macrophage necroptosis in the presence of a caspase inhibitor acting on a non-canonical target(s)

结核分枝杆菌、堪萨斯分枝杆菌和马红球菌在作用于非经典靶点的半胱天冬酶抑制剂存在的情况下，可诱导巨噬细胞坏死性凋亡。

doi:10.1101/2025.09.02.673674

Hu, Rong; Li, Pei; Han, Jie; Huang, Jiamin; Huang, Guoyi; Jiang, Xiuju; Pfau, Daniel; Li, Guobao; Gong, Yi-Nan; Nathan, Carl F; Zhang, Li

细胞生物学

免疫/内分泌

发表日期：2025

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Interferon-γ and infectious diseases: Lessons and prospects

干扰素-γ与传染病：经验教训与展望

影响因子:45.8

doi:10.1126/science.adl2016

Casanova, Jean-Laurent; MacMicking, John D; Nathan, Carl F

发表日期：2024

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Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II

抗疟原虫蛋白酶体抑制剂的构效关系研究——第二部分

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.2c01651

Zhang, Hao; Ginn, John; Zhan, Wenhu; Leung, Annie; Liu, Yi J; Toita, Akinori; Okamoto, Rei; Wong, Tzu-Tshin; Imaeda, Toshihiro; Hara, Ryoma; Michino, Mayako; Yukawa, Takafumi; Chelebieva, Sevil; Tumwebaze, Patrick K; Vendome, Jeremie; Beuming, Thijs; Sato, Kenjiro; Aso, Kazuyoshi; Rosenthal, Philip J; Cooper, Roland A; Liverton, Nigel; Foley, Michael; Meinke, Peter T; Nathan, Carl F; Kirkman, Laura A; Lin, Gang

发表日期：2023

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Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas

基于脒基脲杂环取代的结核分枝杆菌PPT抑制剂

期刊:ACS Medicinal Chemistry Letters

doi:10.1021/acsmedchemlett.3c00162

Ottavi, Samantha; Li, Kelin; Cacioppo, Jackson G; Perkowski, Andrew J; Ramesh, Remya; Gold, Ben S; Ling, Yan; Roberts, Julia; Singh, Amrita; Zhang, David; Mosior, John; Goullieux, Laurent; Roubert, Christine; Bacqué, Eric; Sacchettini, James C; Nathan, Carl F; Aubé, Jeffrey

发表日期：2023

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Transcriptional Biomarkers of Differentially Detectable Mycobacterium tuberculosis in Patient Sputum

患者痰液中差异性可检测结核分枝杆菌的转录生物标志物

影响因子:4.7

doi:10.1128/mbio.02701-22

Zainabadi, Kayvan; Saito, Kohta; Mishra, Saurabh; Walsh, Kathleen Frances; Mathurin, Laurent Daniel; Vilbrun, Stalz Charles; Ocheretina, Oksana; Pape, Jean William; Fitzgerald, Daniel W; Nathan, Carl F; Lee, Myung Hee

发表日期：2022

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Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice

在人源化小鼠中开发具有抗疟活性的高选择性恶性疟原虫蛋白酶体抑制剂

期刊:Angewandte Chemie-International Edition

影响因子:16.9

doi:10.1002/anie.202015845

Zhan, Wenhu; Zhang, Hao; Ginn, John; Leung, Annie; Liu, Yi J; Michino, Mayako; Toita, Akinori; Okamoto, Rei; Wong, Tzu-Tshin; Imaeda, Toshihiro; Hara, Ryoma; Yukawa, Takafumi; Chelebieva, Sevil; Tumwebaze, Patrick K; Lafuente-Monasterio, Maria Jose; Martinez-Martinez, Maria Santos; Vendome, Jeremie; Beuming, Thijs; Sato, Kenjiro; Aso, Kazuyoshi; Rosenthal, Philip J; Cooper, Roland A; Meinke, Peter T; Nathan, Carl F; Kirkman, Laura A; Lin, Gang

发表日期：2021

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Surmounting structural barriers to tackle endemic infectious diseases

克服结构性障碍以应对地方性传染病

期刊:Journal of Experimental Medicine

影响因子:10.6

doi:10.1084/jem.20211418

Calderón, Felix; Fairlamb, Alan H; Strange, Mike; Williams, Pauline; Nathan, Carl F

发表日期：2021

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