日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Author Correction: Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity

作者更正:缺氧诱导中性粒细胞祖细胞组蛋白剪切和H3K4me3丢失,导致中性粒细胞免疫功能长期受损。

Sanchez-Garcia, Manuel A; Sadiku, Pranvera; Ortmann, Brian M; Wit, Niek; Negishi, Yutaka; Coelho, Patricia; Zhang, Ailiang; Pednekar, Chinmayi; Howden, Andrew J M; Griffith, David M; Seear, Rachel; Kindrick, Jessica D; Mengede, Janine; Cooper, George; Morrison, Tyler; Watts, Emily R; Shimeld, Benjamin T; Reyes, Leila; Mirchandani, Ananda S; Arienti, Simone; Xu, Xiang; Thomson, Alexander; Brenes, Alejandro J; Turton, Helena A; Dowey, Rebecca; Hull, Rebecca C; Davidson-Smith, Hazel; McLaren, Amy; Deans, Andrew; Choudhury, Gourab; Doverman, Katherine; Hope, David; Vick, Oliver; Woodhead, Alastair; Petrie, Isla; Green, Suzanne; Rzechorzek, Nina M; Turtle, Lance; Openshaw, Peter J M; Semple, Malcolm G; Sproul, Duncan; Baillie, J Kenneth; Thompson, Alfred A R; Mole, David R; von Kriegsheim, Alex; Whyte, Moira K B; Mhlanga, Musa M; Nathan, James A; Walmsley, Sarah R

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism.

Adaptaquin 通过破坏铁和胆固醇代谢,对神经胶质瘤干细胞具有选择性毒性。

Vaquié Adrien M, Shah Davod R, Brechbühl Eliane E S, McNicholas Michael, Xu Zhaoyang, Stockley John H, Morcom Laura, Gold Diaz Diana, Girdler Gemma C, Seear Rachel V, Balmus Gabriel, Ratan Rajiv R, Bulstrode Harry, Nathan James A, Pathania Manav, Brindle Kevin M, Rowitch David H

Lipoyl deglutarylation by ABHD11 regulates mitochondrial and T cell metabolism.

ABHD11 介导的硫辛酰脱戊二酰化作用调节线粒体和 T 细胞代谢。

Grice Guinevere L, Minogue Eleanor, Coates Hudson W, Debela Mekdes, Stopforth Richard J, Wit Niek, Li Zongyu, Crowley Joseph P, Kaser Arthur, Kaneider-Kaser Nicole, Antrobus P Robin, Haigis Marcia C, Johnson Randall S, Nathan James A

ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity.

ABHD11抑制驱动甾醇代谢,从而调节T细胞效应功能并缓解自身免疫

Jenkins Benjamin J, Jenkins Yasmin R, Ponce-Garcia Fernando M, Moscrop Chloe, Perry Iain A, Hitchings Matthew D, Uribe Alejandro H, Bernuzzi Federico, Eastham Simon, Cronin James G, Berisha Ardena, Howell Alexandra, Davies Joanne, Blagih Julianna, Veale Douglas J, Davies Luke C, Niphakis Micah, Finlay David K, Sinclair Linda V, Cravatt Benjamin F, Hogan Andrew E, Nathan James A, Fearon Ursula, Sumpton David, Vande Voorde Johan, Dias do Vale Goncalo, McDonald Jeffrey G, Jones Gareth W, Pearson James A, Vincent Emma E, Jones Nicholas

A Case of Thrombotic Microangiopathy and Acute Sarcoidosis

一例血栓性微血管病合并急性结节病

Martinelli, Anthony W; Dunn, William; McClure, Mark E; Walker, Ieuan; Stewart, Andrew; Karia, Sumit; Preston, Stephen D; Thiru, Sathia; Torpey, Nicholas; Ojha, Sanjay; Symington, Emily; Nathan, James A

Combined Point-of-Care Nucleic Acid and Antibody Testing for SARS-CoV-2 following Emergence of D614G Spike Variant.

D614G 刺突蛋白变异株出现后,SARS-CoV-2 的即时核酸和抗体联合检测

Mlcochova Petra, Collier Dami, Ritchie Allyson, Assennato Sonny M, Hosmillo Myra, Goel Neha, Meng Bo, Chatterjee Krishna, Mendoza Vivien, Temperton Nigel, Kiss Leo, James Leo C, Ciazynska Katarzyna A, Xiong Xiaoli, Briggs John A G, Nathan James A, Mescia Federica, Bergamaschi Laura, Zhang Hongyi, Barmpounakis Petros, Demeris Nikos, Skells Richard, Lyons Paul A, Bradley John, Baker Steven, Allain Jean Pierre, Smith Kenneth G C, Bousfield Rachel, Wilson Michael, Sparkes Dominic, Amoroso Glenn, Gkrania-Klotsas Effrosyni, Hardwick Susie, Boyle Adrian, Goodfellow Ian, Gupta Ravindra K

Metabolic Regulation of Hypoxia-Inducible Transcription Factors: The Role of Small Molecule Metabolites and Iron

低氧诱导转录因子的代谢调控:小分子代谢物和铁的作用

Bailey, Peter S J; Nathan, James A

Immuno- and constitutive proteasomes do not differ in their abilities to degrade ubiquitinated proteins

免疫蛋白酶体和组成型蛋白酶体在降解泛素化蛋白的能力上没有差异。

Nathan, James A; Spinnenhirn, Valentina; Schmidtke, Gunter; Basler, Michael; Groettrup, Marcus; Goldberg, Alfred L