日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The secretome of senescent monocytes predicts age-related clinical outcomes in humans

衰老单核细胞的分泌组可预测人类与年龄相关的临床结果

Bradley Olinger # ,Reema Banarjee # ,Amit Dey ,Dimitrios Tsitsipatis ,Toshiko Tanaka ,Anjana Ram ,Thedoe Nyunt ,Gulzar N Daya ,Zhongsheng Peng ,Mansi Shrivastava ,Linna Cui ,Julian Candia ,Eleanor M Simonsick ,Myriam Gorospe ,Keenan A Walker ,Luigi Ferrucci ,Nathan Basisty

Substrate Stiffness Dictates Unique Doxorubicin-induced Senescence-associated Secretory Phenotypes and Transcriptomic Signatures in Human Pulmonary Fibroblasts

基质硬度决定了人类肺成纤维细胞中独特的阿霉素诱导的衰老相关分泌表型和转录组特征

Huixun Du, Jacob P Rose, Joanna Bons, Li Guo, Taylor R Valentino, Fei Wu, Jordan B Burton, Nathan Basisty, Max Manwaring-Mueller, Priya Makhijani, Nan Chen, Veronica Chang, Shawn Winer, Judith Campisi, David Furman, Andras Nagy, Birgit Schilling, Daniel A Winer

A plasma proteomic signature links secretome of senescent monocytes to aging- and obesity-related clinical outcomes in humans

血浆蛋白质组学特征将衰老单核细胞的分泌组与人类衰老和肥胖相关的临床结果联系起来

Bradley Olinger, Reema Banarjee, Amit Dey, Dimitrios Tsitsipatis, Toshiko Tanaka, Anjana Ram, Thedoe Nyunt, Gulzar Daya, Zhongsheng Peng, Linna Cui, Julián Candia, Eleanor M Simonsick, Myriam Gorospe, Keenan A Walker, Luigi Ferrucci, Nathan Basisty

Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets

亨廷顿病中型棘状神经元的蛋白质组学分析揭示了脂滴的改变

Kizito-Tshitoko Tshilenge ,Carlos Galicia Aguirre ,Joanna Bons ,Akos A Gerencser ,Nathan Basisty ,Sicheng Song ,Jacob Rose ,Alejandro Lopez-Ramirez ,Swati Naphade ,Ashley Loureiro ,Elena Battistoni ,Mateus Milani ,Cameron Wehrfritz ,Anja Holtz ,Claudio Hetz ,Sean D Mooney ,Birgit Schilling ,Lisa M Ellerby

The transcription regulator ATF4 is a mediator of skeletal muscle aging

转录调节因子 ATF4 是骨骼肌衰老的介质

Matthew J Miller, George R Marcotte, Nathan Basisty, Cameron Wehrfritz, Zachary C Ryan, Matthew D Strub, Andrew T McKeen, Jennifer I Stern, Karl A Nath, Blake B Rasmussen, Andrew R Judge, Birgit Schilling, Scott M Ebert, Christopher M Adams

TurnoveR: A Skyline External Tool for Analysis of Protein Turnover in Metabolic Labeling Studies

TurnoveR:用于代谢标记研究中蛋白质周转分析的 Skyline 外部工具

Nathan Basisty, Nicholas Shulman, Cameron Wehrfritz, Alexandra N Marsh, Samah Shah, Jacob Rose, Scott Ebert, Matthew Miller, Dao-Fu Dai, Peter S Rabinovitch, Christopher M Adams, Michael J MacCoss, Brendan MacLean, Birgit Schilling

Data-independent acquisition and quantification of extracellular matrix from human lung in chronic inflammation-associated carcinomas

慢性炎症相关癌症中人肺细胞外基质的数据独立采集和量化

Joanna Bons, Deng Pan, Samah Shah, Rosemary Bai, Chira Chen-Tanyolac, Xianhong Wang, Daffolyn R Fels Elliott, Anatoly Urisman, Amy O'Broin, Nathan Basisty, Jacob Rose, Veena Sangwan, Sophie Camilleri-Broët, James Tankel, Philippe Gascard, Lorenzo Ferri, Thea D Tlsty, Birgit Schilling

Surfaceome analysis of extracellular vesicles from senescent cells uncovers uptake repressor DPP4

衰老细胞外囊泡的表面组分析揭示了摄取抑制因子 DPP4

Qiong Meng, Chen Chen, Na Yang, Olesia Gololobova, Changyou Shi, Christopher A Dunn, Martina Rossi, Jennifer L Martindale, Nathan Basisty, Jun Ding, Michael Delannoy, Srikanta Basu, Krystyna Mazan-Mamczarz, Chang Hoon Shin, Jen-Hao Yang, Peter F Johnson, Kenneth W Witwer, Arya Biragyn, Payel Sen, Ko

Quantitative Proteomic Analysis of the Senescence-Associated Secretory Phenotype by Data-Independent Acquisition

通过数据独立采集对衰老相关分泌表型进行定量蛋白质组学分析

Francesco Neri, Nathan Basisty, Pierre-Yves Desprez, Judith Campisi, Birgit Schilling

Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

衰老细胞通过激活CD38+巨噬细胞促进组织中NAD+的减少。

Anthony J Covarrubias ,Abhijit Kale # ,Rosalba Perrone # ,Jose Alberto Lopez-Dominguez ,Angela Oliveira Pisco ,Herbert G Kasler ,Mark S Schmidt ,Indra Heckenbach ,Ryan Kwok ,Christopher D Wiley ,Hoi-Shan Wong ,Eddy Gibbs ,Shankar S Iyer ,Nathan Basisty ,Qiuxia Wu ,Ik-Jung Kim ,Elena Silva ,Kaitlyn Vitangcol ,Kyong-Oh Shin ,Yong-Moon Lee ,Rebeccah Riley ,Issam Ben-Sahra ,Melanie Ott ,Birgit Schilling ,Morten Scheibye-Knudsen ,Katsuhiko Ishihara ,Stephen R Quake ,John Newman ,Charles Brenner ,Judith Campisi ,Eric Verdin