Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults
开发用于治疗蛇咬伤中毒的口服乌尼硫醇方案:一项针对健康肯尼亚成年人的 1 期开放标签剂量递增安全性试验和药代动力学分析
期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2025.105600
Abouyannis, Michael; Nyambura, Yvonne K; Ngome, Samson; Riako, Debra; Musyoki, Jennifer; Muiruri, Charles; Orindi, Benedict; Else, Laura; Amara, Alieu; Dickinson, Laura; Clare, Rachel H; Albulescu, Laura-Oana; Westhorpe, Adam P; Kool, Jeroen; Adetifa, Ifedayo; Ndungu, Francis M; FitzGerald, Richard; Khoo, Saye; Lalloo, David G; Casewell, Nicholas R; Hamaluba, Mainga