日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Second international symposium on the chaperone code, 2023

第二届国际陪护人员守则研讨会,2023年

Buchner, Johannes; Alasady, Milad J; Backe, Sarah J; Blagg, Brian S J; Carpenter, Richard L; Colombo, Giorgio; Gelis, Ioannis; Gewirth, Daniel T; Gierasch, Lila M; Houry, Walid A; Johnson, Jill L; Kang, Byoung Heon; Kao, Aimee W; LaPointe, Paul; Mattoo, Seema; McClellan, Amie J; Neckers, Leonard M; Prodromou, Chrisostomos; Rasola, Andrea; Sager, Rebecca A; Theodoraki, Maria A; Truman, Andrew W; Truttman, Matthias C; Zachara, Natasha E; Bourboulia, Dimitra; Mollapour, Mehdi; Woodford, Mark R

Dual inhibition of oxidative phosphorylation and glycolysis exerts a synergistic antitumor effect on colorectal and gastric cancer by creating energy depletion and preventing metabolic switch

氧化磷酸化和糖酵解的双重抑制通过造成能量耗竭和阻止代谢转换,对结直肠癌和胃癌发挥协同抗肿瘤作用。

Aisu, Yuki; Oshima, Nobu; Hyodo, Fuminori; Elhelaly, Abdelazim Elsayed; Masuo, Akihiko; Okada, Tomoaki; Hisamori, Shigeo; Tsunoda, Shigeru; Hida, Koya; Morimoto, Tomonori; Miyoshi, Hiroyuki; Taketo, Makoto M; Matsuo, Masayuki; Neckers, Leonard M; Sakai, Yoshiharu; Obama, Kazutaka

Inhibition of NAD+-Dependent Metabolic Processes Induces Cellular Necrosis and Tumor Regression in Rhabdomyosarcoma Models

抑制NAD+依赖性代谢过程可诱导横纹肌肉瘤模型中的细胞坏死和肿瘤消退

McKay-Corkum, Grace B; Collins, Victor J; Yeung, Choh; Ito, Takeshi; Issaq, Sameer H; Holland, David; Vulikh, Ksenia; Zhang, Yiping; Lee, Unsun; Lei, Haiyan; Mendoza, Arnulfo; Shern, Jack F; Yohe, Marielle E; Yamamoto, Kazutoshi; Wilson, Kelli; Ji, Jiuping; Karim, Baktiar O; Thomas, Craig J; Krishna, Murali C; Neckers, Leonard M; Heske, Christine M

HSP90-Specific nIR Probe Identifies Aggressive Prostate Cancers: Translation from Preclinical Models to a Human Phase I Study.

HSP90 特异性近红外探针可识别侵袭性前列腺癌:从临床前模型到人体 I 期研究的转化

Osada Takuya, Crosby Erika J, Kaneko Kensuke, Snyder Joshua C, Ginzel Joshua D, Acharya Chaitanya R, Yang Xiao-Yi, Polascik Thomas J, Spasojevic Ivan, Nelson Rendon C, Hobeika Amy, Hartman Zachary C, Neckers Leonard M, Rogatko Andre, Hughes Philip F, Huang Jiaoti, Morse Michael A, Haystead Timothy, Lyerly H Kim

NMR Methods for Determining Lipid Turnover via Stable Isotope Resolved Metabolomics

利用稳定同位素分辨代谢组学测定脂质周转的核磁共振方法

Lin, Penghui; Dai, Li; Crooks, Daniel R; Neckers, Leonard M; Higashi, Richard M; Fan, Teresa W-M; Lane, Andrew N

Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy.

动态成像显示肿瘤中 LDH 抑制可导致体内代谢快速重编程,并对联合疗法产生敏感性

Oshima Nobu, Ishida Ryo, Kishimoto Shun, Beebe Kristin, Brender Jeffrey R, Yamamoto Kazutoshi, Urban Daniel, Rai Ganesha, Johnson Michelle S, Benavides Gloria, Squadrito Giuseppe L, Crooks Dan, Jackson Joseph, Joshi Abhinav, Mott Bryan T, Shrimp Jonathan H, Moses Michael A, Lee Min-Jung, Yuno Akira, Lee Tobie D, Hu Xin, Anderson Tamara, Kusewitt Donna, Hathaway Helen H, Jadhav Ajit, Picard Didier, Trepel Jane B, Mitchell James B, Stott Gordon M, Moore William, Simeonov Anton, Sklar Larry A, Norenberg Jeffrey P, Linehan W Marston, Maloney David J, Dang Chi V, Waterson Alex G, Hall Matthew, Darley-Usmar Victor M, Krishna Murali C, Neckers Leonard M

Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

热休克蛋白90的扩增和高表达标志着人表皮生长因子受体2阴性乳腺癌的侵袭性表型。

Cheng, Qing; Chang, Jeffrey T; Geradts, Joseph; Neckers, Leonard M; Haystead, Timothy; Spector, Neil L; Lyerly, H Kim

Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2

Hsp90而非Grp94调控新生ErbB2的细胞内运输和稳定性。

Xu, Wanping; Mimnaugh, Edward G; Kim, Jung-Sik; Trepel, Jane B; Neckers, Leonard M