AUM-302, a novel triple PIM/PI3K/mTOR inhibitor, synergizes with RAS inhibition and impedes the growth of pancreatic ductal adenocarcinoma spheroids and organoids
AUM-302 是一种新型的三重 PIM/PI3K/mTOR 抑制剂，可与 RAS 抑制剂协同作用，抑制胰腺导管腺癌球体和类器官的生长。
期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2026.1685433
Wen, Emma; Vera, Catalina; Kesavan, Sahaana; Kouassi, Fatim; LaComb, Joseph F; Zand, Neecki; Tuveson, David A; Habowski, Amber N; Baines, Antonio T; Bialkowska, Agnieszka B
