日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Concurrent loss of LKB1 and KEAP1 enhances SHMT-mediated antioxidant defence in KRAS-mutant lung cancer

LKB1和KEAP1的同时缺失增强了KRAS突变型肺癌中SHMT介导的抗氧化防御。

Hyun Min Lee ,Nefertiti Muhammad ,Elizabeth L Lieu ,Feng Cai ,Jiawei Mu ,Yun-Sok Ha ,Guoshen Cao ,Chamey Suchors ,Kenneth Joves ,Constantinos Chronis ,Kailong Li ,Gregory S Ducker ,Kellen Olszewski ,Ling Cai ,Derek B Allison ,Sara E Bachert ,William R Ewing ,Harvey Wong ,Hyosun Seo ,Isaac Y Kim ,Brandon Faubert ,James Kim ,Jiyeon Kim

RNA interacts with topoisomerase I to adjust DNA topology

RNA与拓扑异构酶I相互作用以调节DNA拓扑结构

Mannan Bhola,Kouki Abe,Paola Orozco,Homa Rahnamoun,Pedro Avila-Lopez,Elijah Taylor,Nefertiti Muhammad,Bei Liu,Prachi Patel,John F Marko,Anne C Starner,Chuan He,Eric L Van Nostrand,Alfonso Mondragón,Shannon M Lauberth

Downstream-of-gene (DoG) transcripts contribute to an imbalance in the cancer cell transcriptome

基因下游 (DoG) 转录本导致癌细胞转录组失衡

Kouki Abe, Brian Maunze, Pedro-Avila Lopez, Jessica Xu, Nefertiti Muhammad, Guang-Yu Yang, David Katz, Yaping Liu, Shannon M Lauberth

The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer

己糖胺生物合成途径是 KRAS/LKB1 突变肺癌的一个可靶向的缺陷

Jiyeon Kim, Hyun Min Lee, Feng Cai, Bookyung Ko, Chendong Yang, Elizabeth L Lieu, Nefertiti Muhammad, Shawn Rhyne, Kailong Li, Mohamed Haloul, Wen Gu, Brandon Faubert, Akash K Kaushik, Ling Cai, Sahba Kasiri, Ummay Marriam, Kien Nham, Luc Girard, Hui Wang, Xiankai Sun, James Kim, John D Minna, Kezib