日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia

GATA2 将干性与急性髓系白血病的化疗耐药性联系起来

Alikarami, Fatemeh; Xie, Hongbo M; Riedel, Simone S; Goodrow, Haley T; Barrett, Declan R; Mahdavi, Leila; Lenard, Alexandra; Chen, Changya; Yamauchi, Taylor; Danis, Etienne; Cao, Zhendong; Tran, Vu L; Jung, Mabel Minji; Li, Yapeng; Huang, Hua; Shi, Junwei; Tan, Kai; Teachey, David T; Bresnick, Emery H; Neff, Tobias A; Bernt, Kathrin M

Phase 1 study of GSK3368715, a type I PRMT inhibitor, in patients with advanced solid tumors

GSK3368715(一种 I 型 PRMT 抑制剂)治疗晚期实体瘤患者的 1 期研究

El-Khoueiry, Anthony B; Clarke, James; Neff, Tobias; Crossman, Tim; Ratia, Nirav; Rathi, Chetan; Noto, Paul; Tarkar, Aarti; Garrido-Laguna, Ignacio; Calvo, Emiliano; Rodón, Jordi; Tran, Ben; O'Dwyer, Peter J; Cuker, Adam; Abdul Razak, Albiruni R

Evaluation of Cardiac Repolarization in the Randomized Phase 2 Study of Intermediate- or High-Risk Smoldering Multiple Myeloma Patients Treated with Daratumumab Monotherapy

在接受达雷妥尤单抗单药治疗的中危或高危冒烟型多发性骨髓瘤患者的随机 II 期研究中评估心脏复极化

Chari, Ajai; Munder, Markus; Weisel, Katja; Jenner, Matthew; Bygrave, Ceri; Petrucci, Maria Teresa; Boccadoro, Mario; Cavo, Michele; van de Donk, Niels W C J; Turgut, Mehmet; Demirkan, Fatih; Karadogan, Ihsan; Libby, Edward; Kleiman, Robert; Kuppens, Steven; Bandekar, Rajesh; Neff, Tobias; Heuck, Christoph; Qi, Ming; Clemens, Pamela L; Goldschmidt, Hartmut

Daratumumab monotherapy for patients with intermediate-risk or high-risk smoldering multiple myeloma: a randomized, open-label, multicenter, phase 2 study (CENTAURUS)

Daratumumab 单药治疗中危或高危冒烟型多发性骨髓瘤患者:一项随机、开放标签、多中心 2 期研究 (CENTAURUS)

Landgren, C Ola; Chari, Ajai; Cohen, Yael C; Spencer, Andrew; Voorhees, Peter; Estell, Jane A; Sandhu, Irwindeep; Jenner, Matthew W; Williams, Catherine; Cavo, Michele; van de Donk, Niels W C J; Beksac, Meral; Moreau, Philippe; Goldschmidt, Hartmut; Kuppens, Steven; Bandekar, Rajesh; Clemens, Pamela L; Neff, Tobias; Heuck, Christoph; Qi, Ming; Hofmeister, Craig C

Activating PAX gene family paralogs to complement PAX5 leukemia driver mutations.

激活 PAX 基因家族旁系同源基因以补充 PAX5 白血病驱动突变

Hart Matthew R, Anderson Donovan J, Porter Christopher C, Neff Tobias, Levin Michael, Horwitz Marshall S

The role of polycomb repressive complex 2 in early T-cell precursor acute lymphoblastic leukemia

多梳抑制复合物2在早期T细胞前体急性淋巴细胞白血病中的作用

Bernt, Kathrin M; Neff, Tobias

Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia

Ezh2 控制早期造血程序以及早期 T 细胞前体急性淋巴细胞白血病中的生长和存活信号传导

Danis, Etienne; Yamauchi, Taylor; Echanique, Kristen; Zhang, Xi; Haladyna, Jessica N; Riedel, Simone S; Zhu, Nan; Xie, Huafeng; Orkin, Stuart H; Armstrong, Scott A; Bernt, Kathrin M; Neff, Tobias

Recent progress toward epigenetic therapies: the example of mixed lineage leukemia

表观遗传疗法的最新进展:以混合谱系白血病为例

Neff, Tobias; Armstrong, Scott A

Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire

通过对细胞表面谱系进行单细胞分析来绘制细胞层级图谱

Guo, Guoji; Luc, Sidinh; Marco, Eugenio; Lin, Ta-Wei; Peng, Cong; Kerenyi, Marc A; Beyaz, Semir; Kim, Woojin; Xu, Jian; Das, Partha Pratim; Neff, Tobias; Zou, Keyong; Yuan, Guo-Cheng; Orkin, Stuart H

Genetic and pharmacologic inhibition of β-catenin targets imatinib-resistant leukemia stem cells in CML

β-catenin 的基因和药理学抑制可靶向慢性粒细胞白血病中伊马替尼耐药的白血病干细胞。

Heidel, Florian H; Bullinger, Lars; Feng, Zhaohui; Wang, Zhu; Neff, Tobias A; Stein, Lauren; Kalaitzidis, Demetrios; Lane, Steven W; Armstrong, Scott A