日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms

SARS-CoV-2 Mpro 的综合适应度景观揭示了病毒耐药机制

Julia M Flynn, Neha Samant, Gily Schneider-Nachum, David T Barkan, Nese Kurt Yilmaz, Celia A Schiffer, Stephanie A Moquin, Dustin Dovala, Daniel N A Bolon

Sequence dependencies and biophysical features both govern cleavage of diverse cut-sites by HIV protease

序列依赖性和生物物理特征均控制 HIV 蛋白酶对不同切割位点的切割

Neha Samant, Gily Nachum, Tenzin Tsepal, Daniel N A Bolon

Identification of a Permissive Secondary Mutation That Restores the Enzymatic Activity of Oseltamivir Resistance Mutation H275Y

鉴定可恢复奥司他韦耐药突变 H275Y 酶活性的允许性二次突变

Li Jiang, Neha Samant, Ping Liu, Mohan Somasundaran, Jeffrey D Jensen, Wayne A Marasco, Timothy F Kowalik, Celia A Schiffer, Robert W Finberg, Jennifer P Wang, Daniel N A Bolon