日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tissue-specific immune and MAPK signatures in models of reduced Progranulin and Western diet.

减少的粒原蛋白和西方饮食模型中的组织特异性免疫和 MAPK 特征。

Merchak Andrea R, de Sousa Rodrigues Maria Elizabeth, Cole Cassandra, Neighbarger Noelle, Bhavsar Nilay, Wallings Rebecca L, Joers Valerie, Chang Jianjun, Kelly Sean D, Sampson Timothy R, Tansey Malú Gámez

RGS10 differentially modulates NFKB subunit transcription and inflammatory cytokine profiles in peritoneal macrophages

RGS10差异性地调节腹膜巨噬细胞中NFKB亚基的转录和炎症细胞因子谱

Posey, Janna E Jernigan; Dheeravath, Kruthika; Cole, Cassandra L; Neighbarger, Noelle K; Menees, Kelly B; Tansey, Malú Gámez

ASO-mediated knock-down of GPNMB in mutant-GRN and in Grn-deficient peripheral myeloid cells disrupts lysosomal function and immune responses.

在突变型 GRN 和 Grn 缺陷型外周髓系细胞中,ASO 介导的 GPNMB 敲低会破坏溶酶体功能和免疫反应

Wallings Rebecca L, Gillett Drew A, Staley Hannah A, Mahn Savanna, Mark Julian, Neighbarger Noelle, Kordasiewicz Holly, Hirst Warren D, Tansey Malú Gámez

The R1441C-Lrrk2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner in mice

R1441C-Lrrk2突变以年龄和性别依赖的方式诱导小鼠髓系免疫细胞耗竭。

Wallings, Rebecca L; McFarland, Karen; Staley, Hannah A; Neighbarger, Noelle; Schaake, Susen; Brüggemann, Norbert; Zittel, Simone; Usnich, Tatiana; Klein, Christine; Sammler, Esther M; Tansey, Malú Gámez

A263 IRONING OUT THE DETAILS: CROHN’S DISEASE PATIENT DERIVED MACROPHAGES ARE MORE SUSCEPTIBLE TO FERROPTOSIS

A263 完善细节:克罗恩病患者来源的巨噬细胞更容易发生铁死亡

Wallings, Rebecca L; Gillett, Drew A; Staley, Hannah A; Mahn, Savanna; Mark, Julian; Neighbarger, Noelle; Kordasiewicz, Holly; Hirst, Warren D; Tansey, Malú Gámez; Nazemidashtarjandi, Saeed; Supple, Matthew D; Boribong, Brittany; Rosado, Nikki; Karabacak, Nezihi Murat; Yonker, Lael; Yarmush, Martin; Goverman, Jeremy; Irimia, Daniel; Sousa, J A; Callejas Pina, B E; Munazza, Y; Wang, A; Raman, M; McKay, D

The R1441C-LRRK2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner

R1441C-LRRK2突变以年龄和性别依赖的方式诱导髓系免疫细胞耗竭。

Wallings, Rebecca; McFarland, Karen; Staley, Hannah; Neighbarger, Noelle; Schaake, Susen; Brueggemann, Norbert; Zittel, Simone; Usnich, Tatiana; Klein, Christine; Sammler, Esther; Tansey, Malu Gamez

RGS10 Attenuates Systemic Immune Dysregulation Induced by Chronic Inflammatory Stress.

RGS10 可减轻慢性炎症应激引起的全身免疫失调

Jernigan Janna E, Staley Hannah A, Baty Zachary, Bolen MacKenzie L, Gomes Beatriz Nuñes, Holt Jenny, Cole Cassandra L, Neighbarger Noelle K, Dheeravath Kruthika, Merchak Andrea R, Menees Kelly B, Coombes Stephen A, Tansey Malú Gámez