日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells

PKD1 通过丝氨酸 491 的磷酸化抑制 AMPKα2 并损害骨骼肌细胞中的胰岛素信号传导

Kimberly A Coughlan, Rudy J Valentine, Bella S Sudit, Katherine Allen, Yossi Dagon, Barbara B Kahn, Neil B Ruderman, Asish K Saha

Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells

敲低 GSK3β 可增加营养丰富的人主动脉内皮细胞中的基础自噬和 AMPK 信号传导

Karen A Weikel, José M Cacicedo, Neil B Ruderman, Yasuo Ido

Pancreatic β-Cell Dysfunction in Diet-Induced Obese Mice: Roles of AMP-Kinase, Protein Kinase Cε, Mitochondrial and Cholesterol Metabolism, and Alterations in Gene Expression

饮食诱导的肥胖小鼠的胰腺 β 细胞功能障碍:AMP-激酶、蛋白激酶 Cε、线粒体和胆固醇代谢以及基因表达改变的作用

Émilie Pepin, Anfal Al-Mass, Camille Attané, Kezhuo Zhang, Julien Lamontagne, Roxane Lussier, S R Murthy Madiraju, Erik Joly, Neil B Ruderman, Robert Sladek, Marc Prentki, Marie-Line Peyot

Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells

葡萄糖和棕榈酸使 AMPK 与人主动脉内皮细胞的自噬分离

Karen A Weikel, José M Cacicedo, Neil B Ruderman, Yasuo Ido

Insulin inhibits AMPK activity and phosphorylates AMPK Ser⁴⁸⁵/⁴⁹¹ through Akt in hepatocytes, myotubes and incubated rat skeletal muscle

胰岛素抑制 AMPK 活性,并通过 Akt 在肝细胞、肌管和培养大鼠骨骼肌中磷酸化 AMPK Ser⁴⁸⁵/⁴⁹¹

Rudy J Valentine, Kimberly A Coughlan, Neil B Ruderman, Asish K Saha

Glucagon-like peptide-1 (GLP-1) analog liraglutide inhibits endothelial cell inflammation through a calcium and AMPK dependent mechanism

胰高血糖素样肽-1 (GLP-1) 类似物利拉鲁肽通过钙和 AMPK 依赖机制抑制内皮细胞炎症

Nadia M Krasner, Yasuo Ido, Neil B Ruderman, Jose M Cacicedo

A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells

二甲双胍引发的 AMPK-SIRT1 信号与高糖暴露的 HepG2 细胞中 p53 蛋白丰度之间的新型反比关系

Lauren E Nelson, Rudy J Valentine, José M Cacicedo, Marie-Soleil Gauthier, Yasuo Ido, Neil B Ruderman

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

SIRT3 通过可逆酶去乙酰化调节线粒体脂肪酸氧化

Matthew D Hirschey, Tadahiro Shimazu, Eric Goetzman, Enxuan Jing, Bjoern Schwer, David B Lombard, Carrie A Grueter, Charles Harris, Sudha Biddinger, Olga R Ilkayeva, Robert D Stevens, Yu Li, Asish K Saha, Neil B Ruderman, James R Bain, Christopher B Newgard, Robert V Farese Jr, Frederick W Alt, C Ro

Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion

脂肪甘油三酯脂肪酶与燃料和非燃料刺激的胰岛素分泌有关

Marie-Line Peyot, Claudiane Guay, Martin G Latour, Julien Lamontagne, Roxane Lussier, Marco Pineda, Neil B Ruderman, Guenter Haemmerle, Rudolf Zechner, Érik Joly, S R Murthy Madiraju, Vincent Poitout, Marc Prentki