Neil D Perkins相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

A Cell-Based Optimised Approach for Rapid and Efficient Gene Editing of Human Pluripotent Stem Cells

基于细胞的人类多能干细胞快速高效基因编辑的优化方法

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms241210266

Sara Cuevas-Ocaña, Jin Ye Yang, Magomet Aushev, George Schlossmacher, Christine E Bear, Nicholas R F Hannan, Neil D Perkins, Janet Rossant, Amy P Wong, Michael A Gray

发育与干细胞

发表日期：2023

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Claspin haploinsufficiency leads to defects in fertility, hyperplasia and an increased oncogenic potential

Claspin 单倍体不足导致生育能力缺陷、增生和致癌潜力增加

期刊:Biochemical Journal

影响因子:4.4

doi:10.1042/BCJ20220101

Suzanne Madgwick, Saimir Luli, Helene Sellier, Jacqueline A Butterworth, Jack Leslie, Adam J Moore, Emma K Corbin, Adrian I Yemm, Robson T Chiremba, Dina Tiniakos, Fiona Oakley, Neil D Perkins, Jill E Hunter

发表日期：2022

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Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells

CHK1 抑制剂耐药 Eµ-Myc 淋巴瘤细胞中 PI3K/AKT 和 RHO/RAC/PAK 信号通路上调

期刊:Biochemical Journal

影响因子:4.4

doi:10.1042/BCJ20220103

Jill E Hunter, Amy E Campbell, Scott Kerridge, Callum Fraser, Nicola L Hannaway, Saimir Luli, Iglika Ivanova, Philip J Brownridge, Jonathan Coxhead, Leigh Taylor, Peter Leary, Megan S R Hasoon, Claire E Eyers, Neil D Perkins

发表日期：2022

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Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance

RelA(p65) Thr505磷酸化位点的突变会破坏DNA复制应激反应，从而导致CHK1抑制剂耐药性。

期刊:Biochemical Journal

影响因子:4.4

doi:10.1042/BCJ20220089

Jill E Hunter # ，Amy E Campbell # ，Jacqueline A Butterworth ，Helene Sellier ，Nicola L Hannaway ，Saimir Luli ，Achilleas Floudas ，Niall S Kenneth ，Adam J Moore ，Philip J Brownridge ，Huw D Thomas ，Jonathan Coxhead ，Leigh Taylor ，Peter Leary ，Megan S R Hasoon ，Andrew M Knight ，Michelle D Garrett ，Ian Collins ，Claire E Eyers ，Neil D Perkins

发表日期：2022

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Increased migration and motility in XIAP-null cells mediated by the C-RAF protein kinase

C-RAF蛋白激酶介导XIAP缺失细胞的迁移和运动能力增强

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-022-11438-8

Lauren G Russell ,Lydia A K Davis ,Jill E Hunter ,Neil D Perkins ,Niall S Kenneth

细胞生物学

发表日期：2022

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Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX12

与联会复合体蛋白 TEX12 体细胞表达相关的着丝粒功能障碍

期刊:Communications Biology

影响因子:5.2

doi:10.1038/s42003-021-02887-4

Sumit Sandhu, Ieng F Sou, Jill E Hunter, Lucy Salmon, Caroline L Wilson, Neil D Perkins, Neil Hunter, Owen R Davies, Urszula L McClurg

细胞生物学

发表日期：2021

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Temporal modulation of the NF-κB RelA network in response to different types of DNA damage

NF-κB RelA 网络对不同类型 DNA 损伤的反应时间调节

期刊:Biochemical Journal

影响因子:4.4

doi:10.1042/BCJ20200627

Amy E Campbell #, Catarina Ferraz Franco #, Ling-I Su, Emma K Corbin, Simon Perkins, Anton Kalyuzhnyy, Andrew R Jones, Philip J Brownridge, Neil D Perkins, Claire E Eyers

发表日期：2021

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Hypoxia induces rapid, STAT3 and ROS dependent, mitochondrial translocation of RelA(p65) and IκBα

缺氧诱导 STAT3 和 ROS 依赖的 RelA(p65) 和 IκBα 快速线粒体易位

期刊:Bioscience Reports

影响因子:3.8

doi:10.1042/BSR20192101

Iglika G Ivanova, Neil D Perkins

发表日期：2019

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RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation

在暴露于高剂量电离辐射的细胞中，RRAD、IL4I1、CDKN1A 和 SERPINE1 基因可能由 NF-κB 和 p53 转录因子共同调控

期刊:BMC Genomics

影响因子:3.5

doi:10.1186/s12864-018-5211-y

Katarzyna Szołtysek, Patryk Janus, Gracjana Zając, Tomasz Stokowy, Anna Walaszczyk, Wiesława Widłak, Bartosz Wojtaś, Bartłomiej Gielniewski, Simon Cockell, Neil D Perkins, Marek Kimmel, Piotr Widlak

发表日期：2018

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NF-κB is a critical mediator of BRCA1-induced chemoresistance

NF-κB 是 BRCA1 诱导化疗耐药的关键介质

期刊:Oncogene

影响因子:6.9

doi:10.1038/onc.2013.10

Mary T Harte #, Julia J Gorski #, Kienan I Savage, James W Purcell, Eliana M Barros, Philip M Burn, Cheryl McFarlane, Paul B Mullan, Richard D Kennedy, Neil D Perkins, D Paul Harkin

发表日期：2014

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