Neil L Spector相关文献与解析，生知库 | 链接生命科学的每一步

Selective ERBB2 and BCL2 Inhibition Is Synergistic for Mitochondrial-Mediated Apoptosis in MDS and AML Cells

选择性 ERBB2 和 BCL2 抑制对 MDS 和 AML 细胞中的线粒体介导的细胞凋亡具有协同作用

Angel Y F Kam, Sadhna O Piryani, Chang-Lung Lee, David A Rizzieri, Neil L Spector, Stefanie Sarantopoulos, Phuong L Doan

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Photo-activated psoralen binds the ErbB2 catalytic kinase domain, blocking ErbB2 signaling and triggering tumor cell apoptosis

光激活补骨脂素与 ErbB2 催化激酶结构域结合，阻断 ErbB2 信号传导并引发肿瘤细胞凋亡

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0088983

Wenle Xia, David Gooden, Leihua Liu, Sumin Zhao, Erik J Soderblom, Eric J Toone, Wayne F Beyer Jr, Harold Walder, Neil L Spector

An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models

HERGULIN-EGFR-HER3 自分泌信号轴可介导 HER2+ 乳腺癌模型中拉帕替尼获得性耐药

期刊:Breast Cancer Research

影响因子:6.1

doi:10.1186/bcr3480

Wenle Xia, Emanual F Petricoin 3rd, Sumin Zhao, Leihua Liu, Takuya Osada, Qing Cheng, Julia D Wulfkuhle, William R Gwin, Xiaoyi Yang, Rosa I Gallagher, Sarah Bacus, H Kim Lyerly, Neil L Spector

A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53

E3 泛素连接酶 MDM2 和 HUWE1 的底物网络独立于 p53 控制细胞凋亡

期刊:Science Signaling

影响因子:

doi:10.1126/scisignal.2003741

Manabu Kurokawa, Jiyeon Kim, Joseph Geradts, Kenkyo Matsuura, Liu Liu, Xu Ran, Wenle Xia, Thomas J Ribar, Ricardo Henao, Mark W Dewhirst, Wun-Jae Kim, Joseph E Lucas, Shaomeng Wang, Neil L Spector, Sally Kornbluth

Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells

人类 EGF 受体 2/EGF 受体酪氨酸激酶抑制剂激活 AMP 活化蛋白激酶保护心脏细胞

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.0701286104

Neil L Spector, Yosef Yarden, Bradley Smith, Ljuba Lyass, Patricia Trusk, Karen Pry, Jason E Hill, Wenle Xia, Rony Seger, Sarah S Bacus

Visualizing Borrelia burgdorferi Infection Using a Small-Molecule Imaging Probe

利用小分子成像探针可视化伯氏疏螺旋体感染

Selective ERBB2 and BCL2 Inhibition Is Synergistic for Mitochondrial-Mediated Apoptosis in MDS and AML Cells

选择性 ERBB2 和 BCL2 抑制对 MDS 和 AML 细胞中的线粒体介导的细胞凋亡具有协同作用

Photo-activated psoralen binds the ErbB2 catalytic kinase domain, blocking ErbB2 signaling and triggering tumor cell apoptosis

光激活补骨脂素与 ErbB2 催化激酶结构域结合，阻断 ErbB2 信号传导并引发肿瘤细胞凋亡

An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models

HERGULIN-EGFR-HER3 自分泌信号轴可介导 HER2+ 乳腺癌模型中拉帕替尼获得性耐药

A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53

E3 泛素连接酶 MDM2 和 HUWE1 的底物网络独立于 p53 控制细胞凋亡

Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells

人类 EGF 受体 2/EGF 受体酪氨酸激酶抑制剂激活 AMP 活化蛋白激酶保护心脏细胞