日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Induction of the TEAD Coactivator VGLL1 by Estrogen Receptor-Targeted Therapy Drives Resistance in Breast Cancer

雌激素受体靶向治疗诱导 TEAD 辅激活因子 VGLL1 导致乳腺癌产生耐药性

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-24-0013
Carolina Gemma, Chun-Fui Lai, Anup K Singh, Antonino Belfiore, Neil Portman, Heloisa Z Milioli, Manikandan Periyasamy, Sara Raafat, Alyssa J Nicholls, Claire M Davies, Naina R Patel, Georgia M Simmons, Hailing Fan, Van T M Nguyen, Luca Magnani, Emad Rakha, Lesley-Ann Martin, Elgene Lim, R Charles Co
肿瘤
乳腺癌
发表日期：2024
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Co-targeting CDK4/6 and AKT with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer

CDK4/6 和 AKT 与内分泌疗法共同靶向可阻止 CDK4/6 抑制剂和内分泌疗法耐药性乳腺癌的进展

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-021-25422-9
Carla L Alves, Sidse Ehmsen #, Mikkel G Terp #, Neil Portman, Martina Tuttolomondo, Odd L Gammelgaard, Monique F Hundebøl, Kamila Kaminska, Lene E Johansen, Martin Bak, Gabriella Honeth, Ana Bosch, Elgene Lim, Henrik J Ditzel
信号转导
肿瘤
乳腺癌
IHC
WB
PI3K/Akt
发表日期：2021
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DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity

DNA甲基化是维持DNA复制时间精度和3D基因组组织完整性的必要条件

期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2021.109722
Qian Du, Grady C Smith, Phuc Loi Luu, James M Ferguson, Nicola J Armstrong, C Elizabeth Caldon, Elyssa M Campbell, Shalima S Nair, Elena Zotenko, Cathryn M Gould, Michael Buckley, Kee-Ming Chia, Neil Portman, Elgene Lim, Dominik Kaczorowski, Chia-Ling Chan, Kirston Barton, Ira W Deveson, Martin A Sm
信号转导
表观遗传
DNA甲基化
发表日期：2021
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Synergistic targeting of BRCA1 mutated breast cancers with PARP and CDK2 inhibition

PARP 和 CDK2 抑制协同靶向治疗 BRCA1 突变乳腺癌

期刊:NPJ Breast Cancer
影响因子:6.5
doi:10.1038/s41523-021-00312-x
Diar Aziz, Neil Portman, Kristine J Fernandez, Christine Lee, Sarah Alexandrou, Alba Llop-Guevara, Zoe Phan, Aliza Yong, Ashleigh Wilkinson, C Marcelo Sergio, Danielle Ferraro, Dariush Etemadmoghadam, David D Bowtell; kConFab Investigators; Violeta Serra, Paul Waring, Elgene Lim, C Elizabeth Caldon
肿瘤
乳腺癌
WB
发表日期：2021
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MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer

MDM2抑制剂联合内分泌治疗和CDK4/6抑制剂治疗ER阳性乳腺癌

期刊:Breast Cancer Research
影响因子:6.1
doi:10.1186/s13058-020-01318-2
Neil Portman ，Heloisa H Milioli ，Sarah Alexandrou ，Rhiannon Coulson ，Aliza Yong ，Kristine J Fernandez ，Kee Ming Chia ，Ensar Halilovic ，Davendra Segara ，Andrew Parker ，Sue Haupt ，Ygal Haupt ，Wayne D Tilley ，Alex Swarbrick ，C Elizabeth Caldon ，Elgene Lim
MDM2
乳腺癌
CDK4
肿瘤
肿瘤免疫
发表日期：2020
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Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer

靶向混杂异二聚化可克服乳腺癌对 ERBB2 二聚化抑制剂的先天耐药性

期刊:Breast Cancer Research
影响因子:6.1
doi:10.1186/s13058-019-1127-y
Sean P Kennedy, Jeremy Z R Han, Neil Portman, Max Nobis, Jordan F Hastings, Kendelle J Murphy, Sharissa L Latham, Antonia L Cadell, Dushan Miladinovic, Gabriella R Marriott, Yolande E I O'Donnell, Robert F Shearer, James T Williams, Amaya Garcia Munoz, Thomas R Cox, D Neil Watkins, Darren N Saunders
肿瘤
乳腺癌
FCM
IF
IHC-P
WB
GRB2
发表日期：2019
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Non-canonical AR activity facilitates endocrine resistance in breast cancer

非经典 AR 活性促进乳腺癌的内分泌抵抗

期刊:Endocrine-Related Cancer
影响因子:4.1
doi:10.1530/ERC-18-0333
KeeMing Chia, Heloisa Milioli, Neil Portman, Geraldine Laven-Law, Rhiannon Coulson, Aliza Yong, Davendra Segara, Andrew Parker, Catherine E Caldon, Niantao Deng, Alexander Swarbrick, Wayne D Tilley, Theresa E Hickey, Elgene Lim
肿瘤
乳腺癌
ICC-IF
WB
发表日期：2019
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Protein diversity in discrete structures at the distal tip of the trypanosome flagellum

锥虫鞭毛远端离散结构的蛋白质多样性

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.1703553114
Vladimir Varga, Flavia Moreira-Leite, Neil Portman, Keith Gull
信号转导
发表日期：2017
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Combining RNA interference mutants and comparative proteomics to identify protein components and dependences in a eukaryotic flagellum

结合 RNA 干扰突变体和比较蛋白质组学来鉴定真核鞭毛中的蛋白质成分和依赖性

期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1074/jbc.M808859200
Neil Portman, Sylvain Lacomble, Benjamin Thomas, Paul G McKean, Keith Gull
发表日期：2009
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