日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2

通过直接向脑实质注射表达 CLN2 的 rh.10 腺相关病毒来减缓晚期婴儿巴顿病

Dolan Sondhi, Stephen M Kaminsky, Neil R Hackett, Odelya E Pagovich, Jonathan B Rosenberg, Bishnu P De, Alvin Chen, Benjamin Van de Graaf, Jason G Mezey, Grace W Mammen, Denesy Mancenido, Fang Xu, Barry Kosofsky, Kaleb Yohay, Stefan Worgall, Robert J Kaner, Mark Souwedaine, Bruce M Greenwald, Michae

Smoking accelerates aging of the small airway epithelium

吸烟加速小气道上皮细胞的老化

Matthew S Walters, Bishnu P De, Jacqueline Salit, Lauren J Buro-Auriemma, Timothy Wilson, Allison M Rogalski, Lindsay Lief, Neil R Hackett, Michelle R Staudt, Ann E Tilley, Ben-Gary Harvey, Robert J Kaner, Jason G Mezey, Beth Ashbridge, Malcolm A S Moore, Ronald G Crystal

Partial correction of the CNS lysosomal storage defect in a mouse model of juvenile neuronal ceroid lipofuscinosis by neonatal CNS administration of an adeno-associated virus serotype rh.10 vector expressing the human CLN3 gene

通过在新生儿中枢神经系统 (CNS) 中注射表达人类 CLN3 基因的腺相关病毒血清型 rh.10 载体,部分纠正幼年神经元蜡样脂褐素沉积症小鼠模型中的中枢神经系统溶酶体储存缺陷

Dolan Sondhi, Emma C Scott, Alvin Chen, Neil R Hackett, Andrew M S Wong, Agnieszka Kubiak, Hemanth R Nelvagal, Yewande Pearse, Susan L Cotman, Jonathan D Cooper, Ronald G Crystal

Exome sequencing identifies potential risk variants for Mendelian disorders at high prevalence in Qatar

外显子组测序在卡塔尔发现了高发的孟德尔遗传病潜在风险变异

Juan L Rodriguez-Flores ,Khalid Fakhro, Neil R Hackett, Jacqueline Salit, Jennifer Fuller, Francisco Agosto-Perez, Maey Gharbiah, Joel A Malek, Mahmoud Zirie, Amin Jayyousi, Ramin Badii, Ajayeb Al-Nabet Al-Marri, Lotfi Chouchane, Dora J Stadler, Jason G Mezey, Ronald G Crystal

Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells

气道基底细胞血管内皮生长因子介导的串扰调节人类气道基底细胞的内皮细胞依赖性生长支持

Giacomo Curradi, Matthew S Walters, Bi-Sen Ding, Shahin Rafii, Neil R Hackett, Ronald G Crystal

Correction of brain oligodendrocytes by AAVrh.10 intracerebral gene therapy in metachromatic leukodystrophy mice

AAVrh.10 脑内基因治疗对异染性脑白质营养不良小鼠脑少突胶质细胞的矫正

Françoise Piguet, Dolan Sondhi, Monique Piraud, Françoise Fouquet, Neil R Hackett, Ornella Ahouansou, Marie-Thérèse Vanier, Ivan Bieche, Patrick Aubourg, Ronald G Crystal, Nathalie Cartier, Caroline Sevin

Long-term expression and safety of administration of AAVrh.10hCLN2 to the brain of rats and nonhuman primates for the treatment of late infantile neuronal ceroid lipofuscinosis

将 AAVrh.10hCLN2 注射到大鼠和非人灵长类动物的脑中,长期表达并安全性评价其治疗晚期婴儿神经元蜡样脂褐素沉积症

Dolan Sondhi, Linda Johnson, Keith Purpura, Sebastien Monette, Mark M Souweidane, Michael G Kaplitt, Barry Kosofsky, Kaleb Yohay, Douglas Ballon, Jonathan Dyke, Stephen M Kaminksy, Neil R Hackett, Ronald G Crystal

Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs

可卡因类似物与破坏的腺病毒偶联:一种激发对成瘾药物高滴度免疫力的疫苗策略

Martin J Hicks, Bishnu P De, Jonathan B Rosenberg, Jesse T Davidson, Amira Y Moreno, Kim D Janda, Sunmee Wee, George F Koob, Neil R Hackett, Stephen M Kaminsky, Stefan Worgall, Miklos Toth, Jason G Mezey, Ronald G Crystal

The human airway epithelial basal cell transcriptome

人类气道上皮基底细胞转录组

Neil R Hackett, Renat Shaykhiev, Matthew S Walters, Rui Wang, Rachel K Zwick, Barbara Ferris, Bradley Witover, Jacqueline Salit, Ronald G Crystal

Down-regulation of the canonical Wnt β-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD

健康吸烟者和患有 COPD 的吸烟者气道上皮中经典 Wnt β-catenin 通路下调

Rui Wang, Joumana Ahmed, Guoqing Wang, Ibrahim Hassan, Yael Strulovici-Barel, Neil R Hackett, Ronald G Crystal