Neiswender相关文献与解析，生知库 | 链接生命科学的每一步

Venkadakrishnan Varadha Balaji, Presser Adam, Voss Nathaniel C E, Neiswender James, Brenan Lisa, Sosa Keira Prenza, Weng Kenny, Acosta Andres M, Vazquez Francisca, Beltran Himisha

前列腺癌

神经科学

发表日期：2025

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Dominant spinal muscular atrophy linked mutations in the cargo binding domain of BICD2 result in altered interactomes and dynein hyperactivity

BICD2货物结合域中与显性脊髓性肌萎缩症相关的突变会导致相互作用组改变和动力蛋白过度活跃。

期刊:

影响因子:

doi:10.1101/2025.05.13.653647

Neiswender, Hannah; Pride, Jessica E; Veeranan-Karmegam, Rajalakshmi; Allen, Phylicia; Neiswender, Grace; Prabakar, Avneesh; Hao, Caili; Fan, Xingjun; Gonsalvez, Graydon B

CDK12 loss drives prostate cancer progression, transcription-replication conflicts, and synthetic lethality with paralog CDK13

CDK12 缺失驱动前列腺癌进展、转录-复制冲突以及与旁系同源基因 CDK13 的合成致死性

期刊:Cell Reports Medicine

影响因子:11.7

doi:10.1016/j.xcrm.2024.101758

Jean Ching-Yi Tien ，Jie Luo ，Yu Chang ，Yuping Zhang ，Yunhui Cheng ，Xiaoju Wang ，Jianzhang Yang ，Rahul Mannan ，Somnath Mahapatra ，Palak Shah ，Xiao-Ming Wang ，Abigail J Todd ，Sanjana Eyunni ，Caleb Cheng ，Ryan J Rebernick ，Lanbo Xiao ，Yi Bao ，James Neiswender ，Rachel Brough ，Stephen J Pettitt ，Xuhong Cao ，Stephanie J Miner ，Licheng Zhou ，Yi-Mi Wu ，Estefania Labanca ，Yuzhuo Wang ，Abhijit Parolia ，Marcin Cieslik ，Dan R Robinson ，Zhen Wang ，Felix Y Feng ，Jonathan Chou ，Christopher J Lord ，Ke Ding ，Arul M Chinnaiyan

CDK12 Loss Promotes Prostate Cancer Development While Exposing Vulnerabilities to Paralog-Based Synthetic Lethality

CDK12 缺失会促进前列腺癌的发展，同时暴露出基于旁系同源物的合成致死性的弱点

期刊:

影响因子:

doi:10.1101/2024.03.20.585990

Jean Ching-Yi Tien, Yu Chang, Yuping Zhang, Jonathan Chou, Yunhui Cheng, Xiaoju Wang, Jianzhang Yang, Rahul Mannan, Palak Shah, Xiao-Ming Wang, Abigail J Todd, Sanjana Eyunni, Caleb Cheng, Ryan J Rebernick, Lanbo Xiao, Yi Bao, James Neiswender, Rachel Brough, Stephen J Pettitt, Xuhong Cao, Stephanie

肿瘤

前列腺癌

Functional/Block/Neutralize

Pigment cell progenitor heterogeneity and reiteration of developmental signaling underlie melanocyte regeneration in zebrafish

色素细胞祖细胞异质性和发育信号的重复是斑马鱼黑素细胞再生的基础

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.78942

William Tyler Frantz, Sharanya Iyengar, James Neiswender, Alyssa Cousineau, René Maehr, Craig J Ceol

信号转导

其它细胞

Developmental Biology

发表日期：2023

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dTtc1, a conserved tetratricopeptide repeat protein, is required for maturation of Drosophila egg chambers via its role in stabilizing electron transport chain components

dTtc1是一种保守的四肽重复序列蛋白，它通过稳定电子传递链组分，在果蝇卵室的成熟过程中发挥重要作用。

期刊:Frontiers in Cell and Developmental Biology

影响因子:4.3

doi:10.3389/fcell.2023.1148773

Neiswender, Hannah; Baker, Frederick C; Veeranan-Karmegam, Rajalakshmi; Allen, Phylicia; Gonsalvez, Graydon B

Drosophila

发表日期：2023

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In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor

体内邻近生物素连接可识别 Egalitarian 的相互作用组，这是一种动力蛋白货物适配器

期刊:Development

影响因子:3.7

doi:10.1242/dev.199935

Frederick C Baker, Hannah Neiswender, Rajalakshmi Veeranan-Karmegam, Graydon B Gonsalvez

信号转导

发表日期：2021

文献求助收藏

Optimal RNA binding by Egalitarian, a Dynein cargo adaptor, is critical for maintaining oocyte fate in Drosophila

Egalitarian（一种动力蛋白货物适配器）的最佳 RNA 结合对于维持果蝇卵母细胞的命运至关重要

期刊:RNA Biology

影响因子:3.6

doi:10.1080/15476286.2021.1914422

Chandler H Goldman, Hannah Neiswender, Frederick Baker, Rajalakshmi Veeranan-Karmegam, Saurav Misra, Graydon B Gonsalvez

Dynein light chain-dependent dimerization of Egalitarian is essential for maintaining oocyte fate in Drosophila

依赖运动蛋白轻链的 Egalitarian 二聚化对于维持果蝇卵母细胞的命运至关重要

期刊:Developmental Biology

影响因子:2.5

doi:10.1016/j.ydbio.2021.06.009

Hannah Neiswender, Chandler H Goldman, Rajalakshmi Veeranan-Karmegam, Graydon B Gonsalvez

To Be or Not to Be an Oocyte: Msps/XMAP215 Controls Oocyte Cell Fate in the Drosophila Ovary

成为卵母细胞还是不成为卵母细胞：Msps/XMAP215 控制果蝇卵巢中卵母细胞的命运

Epigenetic Derepression of PROX1 Promotes Neuroendocrine Prostate Cancer Progression.

PROX1的表观遗传去抑制促进神经内分泌前列腺癌的进展。

Dominant spinal muscular atrophy linked mutations in the cargo binding domain of BICD2 result in altered interactomes and dynein hyperactivity

BICD2货物结合域中与显性脊髓性肌萎缩症相关的突变会导致相互作用组改变和动力蛋白过度活跃。

CDK12 loss drives prostate cancer progression, transcription-replication conflicts, and synthetic lethality with paralog CDK13

CDK12 缺失驱动前列腺癌进展、转录-复制冲突以及与旁系同源基因 CDK13 的合成致死性

CDK12 Loss Promotes Prostate Cancer Development While Exposing Vulnerabilities to Paralog-Based Synthetic Lethality

CDK12 缺失会促进前列腺癌的发展，同时暴露出基于旁系同源物的合成致死性的弱点

Pigment cell progenitor heterogeneity and reiteration of developmental signaling underlie melanocyte regeneration in zebrafish

色素细胞祖细胞异质性和发育信号的重复是斑马鱼黑素细胞再生的基础

dTtc1, a conserved tetratricopeptide repeat protein, is required for maturation of Drosophila egg chambers via its role in stabilizing electron transport chain components

dTtc1是一种保守的四肽重复序列蛋白，它通过稳定电子传递链组分，在果蝇卵室的成熟过程中发挥重要作用。

In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor

体内邻近生物素连接可识别 Egalitarian 的相互作用组，这是一种动力蛋白货物适配器

Optimal RNA binding by Egalitarian, a Dynein cargo adaptor, is critical for maintaining oocyte fate in Drosophila

Egalitarian（一种动力蛋白货物适配器）的最佳 RNA 结合对于维持果蝇卵母细胞的命运至关重要

Dynein light chain-dependent dimerization of Egalitarian is essential for maintaining oocyte fate in Drosophila

依赖运动蛋白轻链的 Egalitarian 二聚化对于维持果蝇卵母细胞的命运至关重要