日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Aberrant striatal firing mediates impulsive decision-making in a mouse model of Parkinson's disease

纹状体异常放电介导帕金森病小鼠模型中的冲动决策

Zhuang, Xiaowen; Lemak, Julia; Sridhar, Sadhana; Nelson, Alexandra B

Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration.

中脑多巴胺神经元的慢性过度激活会导致多巴胺神经元优先退化

Rademacher Katerina, Doric Zak, Haddad Dominik, Mamaligas Aphroditi, Liao Szu-Chi, Creed Rose, Kano Kohei, Chatterton Zac, Fu Yuhong, Garcia Joseph H, Vance Victoria M, Sei Yoshitaka J, Kreitzer Anatol, Halliday Glenda, Nelson Alexandra B, Margolis Elyssa, Nakamura Ken

Repetitive Levodopa Treatment Drives Cell Type-Specific Striatal Adaptations Associated With Progressive Dyskinesia in Parkinsonian Mice.

重复左旋多巴治疗可驱动帕金森病小鼠进行性运动障碍相关的纹状体细胞类型特异性适应

Paz Rodrigo M, Ryan Michael B, Marcott Pamela F, Girasole Allison E, Faryean Joe, Duong Vincent, Sridhar Sadhana, Nelson Alexandra B

Excessive firing of dyskinesia-associated striatal direct pathway neurons is gated by dopamine and excitatory synaptic input.

与运动障碍相关的纹状体直接通路神经元的过度放电受多巴胺和兴奋性突触输入的调控

Ryan Michael B, Girasole Allison E, Flores Andrew J, Twedell Emily L, McGregor Matthew M, Brakaj Rea, Paletzki Ronald F, Hnasko Thomas S, Gerfen Charles R, Nelson Alexandra B

Altered Iron and Microstructure in Huntington's Disease Subcortical Nuclei: Insight From 7T MRI

亨廷顿病皮质下核团中铁元素和微观结构的改变:来自7T磁共振成像的启示

Yao, Jingwen; Morrison, Melanie A; Jakary, Angela; Avadiappan, Sivakami; Rowley, Paul; Glueck, Julia; Driscoll, Theresa; Geschwind, Michael D; Nelson, Alexandra B; Possin, Kathrine L; Xu, Duan; Hess, Christopher P; Lupo, Janine M

The Cerebellar Cognitive Affective/Schmahmann Syndrome Scale in Spinocerebellar Ataxias

脊髓小脑性共济失调中的小脑认知情感/施马曼综合征量表

Selvadurai, Louisa P; Perlman, Susan L; Ashizawa, Tetsuo; Wilmot, George R; Onyike, Chiadi U; Rosenthal, Liana S; Shakkottai, Vikram G; Paulson, Henry L; Subramony, Sub H; Bushara, Khalaf O; Kuo, Sheng-Han; Dietiker, Cameron; Geschwind, Michael D; Nelson, Alexandra B; Gomez, Christopher M; Opal, Puneet; Zesiewicz, Theresa A; Hawkins, Trevor; Yacoubian, Talene A; Nopoulos, Peggy C; Sha, Sharon J; Morrison, Peter E; Figueroa, Karla P; Pulst, Stefan M; Schmahmann, Jeremy D

Striatal lateral inhibition regulates action selection in a mouse model of levodopa-induced dyskinesia

纹状体侧抑制调节左旋多巴诱导运动障碍小鼠模型中的动作选择

Twedell, Emily L; Bair-Marshall, Chloe J; Girasole, Allison E; Scaria, Lara K; Sridhar, Sadhana; Nelson, Alexandra B

Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy

Tau P301S转基因小鼠出现步态和眼球运动障碍,类似于进行性核上性麻痹症

Creed, Rose B; Harris, Scott C; Sridhar, Sadhana; du Lac, Sascha; Zee, David S; Dunn, Felice A; Bouvier, Guy; Nelson, Alexandra B

Comparison of quantitative susceptibility mapping methods for iron-sensitive susceptibility imaging at 7T: An evaluation in healthy subjects and patients with Huntington's disease

7T磁共振成像中铁敏感磁化率定量映射方法的比较:对健康受试者和亨廷顿病患者的评估

Yao, Jingwen; Morrison, Melanie A; Jakary, Angela; Avadiappan, Sivakami; Chen, Yicheng; Luitjens, Johanna; Glueck, Julia; Driscoll, Theresa; Geschwind, Michael D; Nelson, Alexandra B; Villanueva-Meyer, Javier E; Hess, Christopher P; Lupo, Janine M

Striatal Indirect Pathway Dysfunction Underlies Motor Deficits in a Mouse Model of Paroxysmal Dyskinesia

纹状体间接通路功能障碍是阵发性运动障碍小鼠模型运动缺陷的根本原因

Nelson, Alexandra B; Girasole, Allison E; Lee, Hsien-Yang; Ptáček, Louis J; Kreitzer, Anatol C