日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Efficacy of Inhalable Endolysin Cpl-1 Formulations in Combination with Gentamicin or Endolysin Pal in a Murine Lung Infection Model

吸入型溶血素Cpl-1制剂联合庆大霉素或溶血素Pal在小鼠肺部感染模型中的疗效

期刊:Pharmaceutical Research
影响因子:4.3
doi:10.1007/s11095-025-03942-z
Wang, Yuncheng; Stevens, Maxwell T; Wang, Trixie; Alreja, Adit B; Nelson, Daniel C; Britton, Warwick J; Chan, Hak-Kim
炎症/感染
发表日期：2026
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Endolysins: targeting Streptococcus pneumoniae in its major anatomical niches of infection and addressing the hurdles

溶内肽酶：靶向肺炎链球菌的主要感染解剖部位并克服其面临的挑战

期刊:Frontiers in Microbiology
影响因子:4.5
doi:10.3389/fmicb.2025.1660791
Castallanos, Giovanna; Gonzalez-Juarbe, Norberto; Nelson, Daniel C
肺炎
炎症/感染
发表日期：2025
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Harnessing mRNA to unleash endolysins: A new frontier in antibacterial therapy

利用mRNA释放内溶素：抗菌治疗的新前沿

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2024.102249
Nelson, Daniel C; Dave, Urmil M; Gonzalez-Juarbe, Norberto
发表日期：2024
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SP-CHAP, an endolysin with enhanced activity against biofilm pneumococci and nasopharyngeal colonization

SP-CHAP，一种对肺炎球菌生物膜和鼻咽定植具有增强活性的溶菌酶

期刊:mBio
影响因子:4.7
doi:10.1128/mbio.00069-24
Alreja, Adit B; Appel, Amanda E; Zhu, Jinyi C; Riley, Sean P; Gonzalez-Juarbe, Norberto; Nelson, Daniel C
肺炎
微生物学
发表日期：2024
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Engineered antibodies targeted to bacterial surface integrate effector functions with toxin neutralization to provide superior efficacy against bacterial infections

针对细菌表面的工程化抗体整合了效应功能和毒素中和作用，从而对细菌感染具有更优异的疗效。

期刊:
影响因子:
doi:10.1101/2024.09.23.24313920
Adhikari, Rajan P; Alem, Farhang; Kemboi, Daniel; Kanipakala, Tulasikumari; Sherchand, Shardulendra P; Kailasan, Shweta; Purcell, Bret K; Heine, Henry S; Russell-Lodrigue, Kasi; Etobayeva, Irina; Howell, Katie A; Vu, Hong; Shulenin, Sergey; Holtsberg, Frederick W; Roy, Chad J; Hakami, Ramin M; Nelson, Daniel C; Aman, M Javad
炎症/感染
微生物学
发表日期：2024
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A unique borrelial protein facilitates microbial immune evasion

一种独特的伯氏疏螺旋体蛋白有助于微生物逃避免疫攻击

期刊:mBio
影响因子:4.7
doi:10.1128/mbio.02135-23
Foor, Shelby D; Brangulis, Kalvis; Shakya, Anil K; Rana, Vipin S; Bista, Sandhya; Kitsou, Chrysoula; Ronzetti, Michael; Alreja, Adit B; Linden, Sara B; Altieri, Amanda S; Baljinnyam, Bolormaa; Akopjana, Inara; Nelson, Daniel C; Simeonov, Anton; Herzberg, Osnat; Caimano, Melissa J; Pal, Utpal
微生物学
免疫/内分泌
发表日期：2023
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Understanding the Molecular Basis for Homodimer Formation of the Pneumococcal Endolysin Cpl-1

了解肺炎球菌溶血素 Cpl-1 同源二聚体形成的分子基础

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.2c00627
Alreja, Adit B; Linden, Sara B; Lee, Harrison R; Chao, Kinlin L; Herzberg, Osnat; Nelson, Daniel C
肺炎
发表日期：2023
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Thermal Characterization and Interaction of the Subunits from the Multimeric Bacteriophage Endolysin PlyC

多聚体噬菌体溶菌素PlyC亚基的热特性及相互作用

期刊:Biology-Basel
影响因子:3.5
doi:10.3390/biology12101277
Hoopes, J Todd; Heselpoth, Ryan D; Schwarz, Frederick P; Nelson, Daniel C
发表日期：2023
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Structure of Escherichia coli O157:H7 bacteriophage CBA120 tailspike protein 4 baseplate anchor and tailspike assembly domains (TSP4-N)

大肠杆菌 O157:H7 噬菌体 CBA120 尾刺蛋白 4 基板锚定和尾刺组装结构域 (TSP4-N) 的结构

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-022-06073-2
Chao, Kinlin L; Shang, Xiaoran; Greenfield, Julia; Linden, Sara B; Alreja, Adit B; Nelson, Daniel C; Herzberg, Osnat
SP4
发表日期：2022
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Controlled Proteolysis of an Essential Virulence Determinant Dictates Infectivity of Lyme Disease Pathogens

关键毒力决定因子的受控蛋白水解决定了莱姆病病原体的感染性

期刊:Infection and Immunity
影响因子:2.8
doi:10.1128/iai.00059-22
Thakur, Meghna; Bista, Sandhya; Foor, Shelby D; Dutta, Shraboni; Yang, Xiuli; Ronzetti, Michael; Rana, Vipin S; Kitsou, Chrysoula; Linden, Sara B; Altieri, Amanda S; Baljinnyam, Bolormaa; Nelson, Daniel C; Simeonov, Anton; Pal, Utpal
炎症/感染
微生物学
莱姆病
发表日期：2022
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