Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics.
LRRK2 GTPase 结构域中与帕金森病相关的突变会损害其核苷酸依赖性构象动力学
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.RA119.007631
Wu Chun-Xiang, Liao Jingling, Park Yangshin, Reed Xylena, Engel Victoria A, Hoang Neo C, Takagi Yuichiro, Johnson Steven M, Wang Mu, Federici Mark, Nichols R Jeremy, Sanishvili Ruslan, Cookson Mark R, Hoang Quyen Q
