日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes

阿来法塞激动剂作用可促进新发1型糖尿病中TIGIT+PD1+效应记忆CD4 T细胞的早期扩增

期刊:Journal of Immunology
影响因子:3.4
doi:10.1093/jimmun/vkae014
Higdon, Lauren E; Cooney, Laura A; Serti, Elisavet; Suwannasaen, Duangchan; Muir, Virginia S; Wiedeman, Alice E; Harris, Kristina M; Pardo, Jorge; Anderson, Mark S; Speake, Cate; Nepom, Gerald T; Linsley, Peter S; Sanda, Srinath; Long, S Alice
TIGIT
T细胞
T细胞
糖尿病
CD4
免疫/内分泌
代谢
细胞生物学
发表日期：2025
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A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab

一项针对近期发病的1型糖尿病患者的首次人体开放标签1b期临床试验和一项随机双盲2a期临床试验，评估AG019单药治疗以及与teplizumab联合治疗的疗效。

期刊:Diabetologia
影响因子:10.2
doi:10.1007/s00125-023-06014-2
Mathieu, Chantal; Wiedeman, Alice; Cerosaletti, Karen; Long, S Alice; Serti, Elisavet; Cooney, Laura; Vermeiren, Joan; Caluwaerts, Silvia; Van Huynegem, Karolien; Steidler, Lothar; Blomme, Sven; Rottiers, Pieter; Nepom, Gerald T; Herold, Kevan C
糖尿病
代谢
发表日期：2024
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Breakdown and Repair of Peripheral Immune Tolerance in Type 1 Diabetes

1型糖尿病外周免疫耐受的破坏与修复

期刊:Cold Spring Harbor Perspectives in Medicine
影响因子:10.1
doi:10.1101/cshperspect.a041596
Nepom, Gerald T
代谢
糖尿病
免疫/内分泌
发表日期：2024
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Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop

型糖尿病病理生理学、筛查和预防的最新概念：糖尿病机构间协调委员会研讨会报告

期刊:Diabetes
影响因子:7.5
doi:10.2337/dbi24-0020
Greenbaum, Carla J; Nepom, Gerald T; Wood-Heickman, Lauren K; Wherrett, Diane K; DiMeglio, Linda A; Herold, Kevan C; Krischer, Jeffrey P
糖尿病
代谢
发表日期：2024
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Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8(+) T cells beneficial in type 1 diabetes

相互关联的谱系轨迹将常规和自然杀伤 (NK) 样耗竭的 CD8(+) T 细胞联系起来，这些细胞在 1 型糖尿病中发挥有益作用。

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-024-06456-3
Witkop, Erin M; Diggins, Kirsten; Wiedeman, Alice; Serti, Elisavet; Nepom, Gerald; Gersuk, Vivian H; Fuchs, Bryce; Long, S Alice; Linsley, Peter S
T细胞
CD8
代谢
糖尿病
细胞生物学
发表日期：2024
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Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy

接受口服免疫疗法的花生过敏患者体内，抗原特异性T细胞的轨迹各不相同。

期刊:Journal of Allergy and Clinical Immunology
影响因子:11.2
doi:10.1016/j.jaci.2023.03.020
Calise, Justine; DeBerg, Hannah; Garabatos, Nahir; Khosa, Sugandhika; Bajzik, Veronique; Calderon, Lorena Botero; Aldridge, Kelly; Rosasco, Mario; Ferslew, Brian C; Zhu, Tong; Smulders, Ronald; Wheatley, Lisa M; Laidlaw, Tanya M; Qin, Tielin; Chichili, Gurunadh R; Adelman, Daniel C; Farrington, Mary; Robinson, David; Jeong, David; Jones, Stacie M; Sanda, Srinath; Larson, David; Kwok, William W; Baloh, Carolyn; Nepom, Gerald T; Wambre, Erik
细胞生物学
T细胞
T细胞
免疫/内分泌
发表日期：2023
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Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: A randomized controlled trial

tezepelumab联合过敏原免疫疗法对鼻腔过敏原反应的影响：一项随机对照试验

期刊:Journal of Allergy and Clinical Immunology
影响因子:11.2
doi:10.1016/j.jaci.2022.08.029
Corren, Jonathan; Larson, David; Altman, Matthew C; Segnitz, R Max; Avila, Pedro C; Greenberger, Paul A; Baroody, Fuad; Moss, Mark H; Nelson, Harold; Burbank, Allison J; Hernandez, Michelle L; Peden, David; Saini, Sarbjit; Tilles, Stephen; Hussain, Iftikhar; Whitehouse, Don; Qin, Tielin; Villarreal, Miguel; Sever, Michelle; Wheatley, Lisa M; Nepom, Gerald T; Sanda, Srinath
免疫/内分泌
发表日期：2023
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Epidermal differentiation complex genetic variation in atopic dermatitis and peanut allergy

表皮分化复合体基因变异与特应性皮炎和花生过敏有关

期刊:Journal of Allergy and Clinical Immunology
影响因子:11.2
doi:10.1016/j.jaci.2022.11.008
Huffaker, Michelle F; Kanchan, Kanika; Bahnson, Henry T; Ruczinski, Ingo; Shankar, Gautam; Leung, Donald Y M; Baloh, Carolyn; Du Toit, George; Lack, Gideon; Nepom, Gerald T; Mathias, Rasika A
发表日期：2023
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Incorporating genetics in identifying peanut allergy risk and tailoring allergen immunotherapy: A perspective on the genetic findings from the LEAP trial

将遗传学纳入花生过敏风险识别和过敏原免疫疗法定制：基于LEAP试验遗传学发现的视角

期刊:Journal of Allergy and Clinical Immunology
影响因子:11.2
doi:10.1016/j.jaci.2022.12.819
Huffaker, Michelle F; Kanchan, Kanika; Bahnson, Henry T; Baloh, Carolyn; Lack, Gideon; Nepom, Gerald T; Mathias, Rasika A
免疫/内分泌
发表日期：2023
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Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes

胰岛自身反应性 CD4+ T 细胞与 1 型糖尿病对阿法赛普的反应有关

期刊:JCI Insight
影响因子:6.3
doi:10.1172/jci.insight.167881
Elisa Balmas, Janice Chen, Alex K Hu, Hannah A DeBerg, Mario G Rosasco, Vivian H Gersuk, Elisavet Serti, Cate Speake, Carla J Greenbaum, Gerald T Nepom, Peter S Linsley, Karen Cerosaletti
免疫
细胞生物学
糖尿病
T细胞
发表日期：2023
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