日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A genome-wide CRISPR activation screen reveals Hexokinase 1 as a critical factor in promoting resistance to multi-kinase inhibitors in hepatocellular carcinoma cells

全基因组 CRISPR 激活筛选揭示己糖激酶 1 是促进肝细胞癌细胞对多激酶抑制剂产生耐药性的关键因素

Summer Sofer, Kevin Lamkiewicz, Shir Armoza Eilat, Shirly Partouche, Manja Marz, Neta Moskovits, Salomon M Stemmer, Amir Shlomai, Ella H Sklan

Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models

抑制成纤维细胞分泌的 QSOX1 会扰乱肿瘤微环境中的细胞外基质,并降低小鼠癌症模型中的肿瘤生长和转移

Tal Feldman, Iris Grossman-Haham, Yoav Elkis, Patrick Vilela, Neta Moskovits, Iris Barshack, Tomer M Salame, Deborah Fass, Tal Ilani

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

组蛋白 H2B 特异性泛素连接酶 RNF20/hBRE1 通过选择性调控基因表达,发挥假定的肿瘤抑制因子作用

Efrat Shema, Itay Tirosh, Yael Aylon, Jing Huang, Chaoyang Ye, Neta Moskovits, Nina Raver-Shapira, Neri Minsky, Judith Pirngruber, Gabi Tarcic, Pavla Hublarova, Lilach Moyal, Mali Gana-Weisz, Yosef Shiloh, Yossef Yarden, Steven A Johnsen, Borivoj Vojtesek, Shelley L Berger, Moshe Oren