日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting histone deacetylation, cell cycle regulators and heat shock proteins as novel therapeutic strategies for penile cancers

靶向组蛋白去乙酰化、细胞周期调节因子和热休克蛋白作为阴茎癌的新型治疗策略

Marson, Lara; Skowron, Margaretha A; Pongratanakul, Pailin; Kotthoff, Mara; Poschmann, Gereon; Bohnenberger, Hanibal; Stephan, Alexa; Watolla, Meike M; Mukinovic, Elvira; Stühler, Kai; Kurz, Thomas; Ayoubian, Hiresh; Linxweiler, Johannes; Junker, Kerstin; Nettersheim, Daniel

Molecular pathology of testicular germ cell tumours: an update for practicing pathologists

睾丸生殖细胞肿瘤的分子病理学:病理医师实践指南

Fichtner, Alexander; Zschäbitz, Stefanie; Nettersheim, Daniel; Bremmer, Felix

Valproic Acid Confers Functional Pluripotency to Human Amniotic Fluid Stem Cells in a Transgene-free Approach

丙戊酸以非转基因方式赋予人羊水干细胞功能性多能性

Moschidou, Dafni; Mukherjee, Sayandip; Blundell, Michael P; Drews, Katharina; Jones, Gemma N; Abdulrazzak, Hassan; Nowakowska, Beata; Phoolchund, Anju; Lay, Kenneth; Ramasamy, T Selvee; Cananzi, Mara; Nettersheim, Daniel; Sullivan, Mark; Frost, Jennifer; Moore, Gudrun; Vermeesch, Joris R; Fisk, Nicholas M; Thrasher, Adrian J; Atala, Anthony; Adjaye, James; Schorle, Hubert; De Coppi, Paolo; Guillot, Pascale V

Molecular characterization of the CXCR4 / CXCR7 axis in germ cell tumors and its targetability using nanobody-drug-conjugates

生殖细胞肿瘤中CXCR4/CXCR7轴的分子特征及其纳米抗体-药物偶联靶向性研究

Wakileh, Gamal A; Bierholz, Philipp; Kotthoff, Mara; Skowron, Margaretha A; Bremmer, Felix; Stephan, Alexa; Anbuhl, Stephanie M; Heukers, Raimond; Smit, Martine J; Ströbel, Philipp; Nettersheim, Daniel

Characterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of therapy resistance, and druggable targets

通过对生殖细胞肿瘤相关体细胞型恶性肿瘤的突变负荷、DNA甲基化图谱和蛋白质组进行表征,以确定其组织起源、治疗耐药机制和药物靶点。

Bremmer, Felix; Pongratanakul, Pailin; Skowron, Margaretha; Che, Yue; Richter, Annika; Küffer, Stefan; Reuter-Jessen, Kirsten; Bohnenberger, Hanibal; Pauls, Stella; Kresbach, Catena; Schüller, Ulrich; Stühler, Kai; Ströbel, Philipp; Albers, Peter; Nettersheim, Daniel

Genome-scale CRISPR screen reveals neddylation to contribute to cisplatin resistance of testicular germ cell tumours

基因组规模的 CRISPR 筛选揭示 neddylation 修饰与睾丸生殖细胞肿瘤的顺铂耐药性有关

Funke, Kai; Einsfelder, Ulf; Hansen, Aylin; Arévalo, Lena; Schneider, Simon; Nettersheim, Daniel; Stein, Valentin; Schorle, Hubert

On the origin of germ cell neoplasia in situ: Dedifferentiation of human adult Sertoli cells in cross talk with seminoma cells in vitro

原位生殖细胞肿瘤的起源:体外人成年睾丸支持细胞与精原细胞瘤细胞相互作用导致的去分化

Fink, Cornelia; Baal, Nelli; Wilhelm, Jochen; Sarode, Poonam; Weigel, Roswitha; Schumacher, Valérie; Nettersheim, Daniel; Schorle, Hubert; Schröck, Carmen; Bergmann, Martin; Kliesch, Sabine; Kressin, Monika; Savai, Rajkumar

The pioneer and differentiation factor FOXA2 is a key driver of yolk-sac tumour formation and a new biomarker for paediatric and adult yolk-sac tumours

先锋分化因子FOXA2是卵黄囊瘤形成的关键驱动因素,也是儿童和成人卵黄囊瘤的新型生物标志物。

Wruck, Wasco; Bremmer, Felix; Kotthoff, Mara; Fichtner, Alexander; Skowron, Margaretha A; Schönberger, Stefan; Calaminus, Gabriele; Vokuhl, Christian; Pfister, David; Heidenreich, Axel; Albers, Peter; Adjaye, James; Nettersheim, Daniel

Molecular and epigenetic pathogenesis of germ cell tumors

生殖细胞肿瘤的分子和表观遗传发病机制

Müller, Melanie R; Skowron, Margaretha A; Albers, Peter; Nettersheim, Daniel

Efficacy of HDAC Inhibitors Belinostat and Panobinostat against Cisplatin-Sensitive and Cisplatin-Resistant Testicular Germ Cell Tumors.

HDAC抑制剂贝利司他和帕比司他治疗顺铂敏感和顺铂耐药睾丸生殖细胞肿瘤的疗效

Lobo João, Guimarães-Teixeira Catarina, Barros-Silva Daniela, Miranda-Gonçalves Vera, Camilo Vânia, Guimarães Rita, Cantante Mariana, Braga Isaac, Maurício Joaquina, Oing Christoph, Honecker Friedemann, Nettersheim Daniel, Looijenga Leendert Hj, Henrique Rui, Jerónimo Carmen