Chronic Treatment with the AMPK Agonist AICAR Prevents Skeletal Muscle Pathology but Fails to Improve Clinical Outcome in a Mouse Model of Severe Spinal Muscular Atrophy

使用 AMPK 激动剂 AICAR 进行长期治疗可预防骨骼肌病变，但无法改善重度脊髓性肌萎缩症小鼠模型的临床结果