日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

LDL-Dependent Regulation of TNFα/PGE2 Induced COX-2/mPGES-1 Expression in Human Macrophage Cell Lines

LDL 依赖性调节 TNFα/PGE2 诱导人类巨噬细胞系中的 COX-2/mPGES-1 表达

Frank Neuschäfer-Rube, Theresa Schön, Ines Kahnt, Gerhard Paul Püschel

Discrimination of the Activity of Low-Affinity Wild-Type and High-Affinity Mutant Recombinant BoNT/B by a SIMA Cell-Based Reporter Release Assay

通过基于 SIMA 细胞的报告基因释放分析区分低亲和力野生型和高亲和力突变重组 BoNT/B 的活性

Frank Neuschäfer-Rube, Andrea Pathe-Neuschäfer-Rube, Gerhard P Püschel

Cell-Based Reporter Release Assay to Determine the Activity of Calcium-Dependent Neurotoxins and Neuroactive Pharmaceuticals

基于细胞的报告基因释放试验用于确定钙依赖性神经毒素和神经活性药物的活性

Andrea Pathe-Neuschäfer-Rube, Frank Neuschäfer-Rube, Gerhard P Püschel

Cell-Based Reporter Release Assay to Determine the Potency of Proteolytic Bacterial Neurotoxins

基于细胞的报告基因释放试验确定蛋白水解细菌神经毒素的效力

Andrea Pathe-Neuschäfer-Rube, Frank Neuschäfer-Rube, Gerald Haas, Nina Langoth-Fehringer, Gerhard Paul Püschel

The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism

人类长寿基因同源物INDY和白细胞介素-6在肝脏脂质代谢中相互作用

von Loeffelholz, Christian; Lieske, Stefanie; Neuschäfer-Rube, Frank; Willmes, Diana M; Raschzok, Nathanael; Sauer, Igor M; König, Jörg; Fromm, Martin F; Horn, Paul; Chatzigeorgiou, Antonios; Pathe-Neuschäfer-Rube, Andrea; Jordan, Jens; Pfeiffer, Andreas F H; Mingrone, Geltrude; Bornstein, Stefan R; Stroehle, Peter; Harms, Christoph; Wunderlich, F Thomas; Helfand, Stephen L; Bernier, Michel; de Cabo, Rafael; Shulman, Gerald I; Chavakis, Triantafyllos; Püschel, Gerhard P; Birkenfeld, Andreas L

The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes

在2型糖尿病大鼠模型中,哺乳动物INDY同源物受CREB诱导表达。

Neuschäfer-Rube, Frank; Lieske, Stefanie; Kuna, Manuela; Henkel, Janin; Perry, Rachel J; Erion, Derek M; Pesta, Dominik; Willmes, Diana M; Brachs, Sebastian; von Loeffelholz, Christian; Tolkachov, Alexander; Schupp, Michael; Pathe-Neuschäfer-Rube, Andrea; Pfeiffer, Andreas F H; Shulman, Gerald I; Püschel, Gerhard P; Birkenfeld, Andreas L

A Ser/Thr cluster within the C-terminal domain of the rat prostaglandin receptor EP3alpha is essential for agonist-induced phosphorylation, desensitization and internalization

大鼠前列腺素受体EP3α C端结构域内的丝氨酸/苏氨酸簇对于激动剂诱导的磷酸化、脱敏和内化至关重要。

Neuschäfer-Rube, Frank; Hermosilla, Ricardo; Kuna, Manuela; Pathe-Neuschäfer-Rube, Andrea; Schülein, Ralf; Püschel, Gerhard Paul

Role of the ERC motif in the proximal part of the second intracellular loop and the C-terminal domain of the human prostaglandin F2alpha receptor (hFP-R) in G-protein coupling control

人前列腺素F2α受体(hFP-R)第二胞内环近端部分和C端结构域中的ERC基序在G蛋白偶联调控中的作用

Pathe-Neuschäfer-Rube, Andrea; Neuschäfer-Rube, Frank; Püschel, Gerhard P

Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin receptor EP4 that is essential for agonist-induced beta-arrestin1 recruitment but differs from the apparent principal phosphorylation site

在人前列腺素受体EP4的C端结构域中鉴定出一个Ser/Thr簇,该簇对于激动剂诱导的β-arrestin1募集至关重要,但与已知的主要磷酸化位点不同。

Neuschäfer-Rube, Frank; Hermosilla, Ricardo; Rehwald, Mathias; Rönnstrand, Lars; Schülein, Ralf; Wernstedt, Christer; Püschel, Gerhard Paul

Identification by site-directed mutagenesis of amino acids contributing to ligand-binding specificity or signal transduction properties of the human FP prostanoid receptor

通过定点诱变鉴定影响人FP前列腺素受体配体结合特异性或信号转导特性的氨基酸

Neuschäfer-Rube, Frank; Engemaier, Eva; Koch, Sina; Böer, Ulrike; Püschel, Gerhard P