日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity

泛素特异性蛋白酶-7抑制会损害Tip60依赖的Foxp3+ T调节细胞功能并促进抗肿瘤免疫

Wang, Liqing; Kumar, Suresh; Dahiya, Satinder; Wang, Feng; Wu, Jian; Newick, Kheng; Han, Rongxiang; Samanta, Arabinda; Beier, Ulf H; Akimova, Tatiana; Bhatti, Tricia R; Nicholson, Benjamin; Kodrasov, Mathew P; Agarwal, Saket; Sterner, David E; Gu, Wei; Weinstock, Joseph; Butt, Tauseef R; Albelda, Steven M; Hancock, Wayne W

Blockade of Programmed Death 1 Augments the Ability of Human T Cells Engineered to Target NY-ESO-1 to Control Tumor Growth after Adoptive Transfer

阻断程序性死亡 1 可增强针对 NY-ESO-1 的人类 T 细胞在过继转移后控制肿瘤生长的能力

Edmund K Moon, Raghuveer Ranganathan, Evgeniy Eruslanov, Soyeon Kim, Kheng Newick, Shaun O'Brien, Albert Lo, Xiaojun Liu, Yangbing Zhao, Steven M Albelda

Augmentation of CAR T-cell Trafficking and Antitumor Efficacy by Blocking Protein Kinase A Localization

通过阻断蛋白激酶A定位增强CAR T细胞迁移和抗肿瘤疗效

Kheng Newick ,Shaun O'Brien ,Jing Sun ,Veena Kapoor ,Steven Maceyko ,Albert Lo ,Ellen Puré ,Edmund Moon ,Steven M Albelda

HDAC5 controls the functions of Foxp3(+) T-regulatory and CD8(+) T cells

HDAC5 控制 Foxp3(+) T 调节细胞和 CD8(+) T 细胞的功能

Haiyan Xiao, Jing Jiao, Liqing Wang, Shaun O'Brien, Kheng Newick, Liang-Chuan S Wang, Eva Falkensammer, Yujie Liu, Rongxiang Han, Veena Kapoor, Finn K Hansen, Thomas Kurz, Wayne W Hancock, Ulf H Beier

Chimeric antigen receptor T-cell therapy for solid tumors

嵌合抗原受体T细胞疗法治疗实体瘤

Newick, Kheng; Moon, Edmund; Albelda, Steven M

Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric Immunoreceptors

使用基于 DAP12 的多链嵌合免疫受体产生针对癌症的强效 T 细胞免疫疗法

Enxiu Wang, Liang-Chuan Wang, Ching-Yi Tsai, Vijay Bhoj, Zack Gershenson, Edmund Moon, Kheng Newick, Jing Sun, Albert Lo, Timothy Baradet, Michael D Feldman, David Barrett, Ellen Puré, Steven Albelda, Michael C Milone

Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma

通过过氧化物酶 3 的组合靶向抑制线粒体过氧化物代谢是治疗恶性间皮瘤的有效方法

Brian Cunniff, Kheng Newick, Kimberly J Nelson, Alexandra N Wozniak, Stacie Beuschel, Bruce Leavitt, Anant Bhave, Kelly Butnor, Andreas Koenig, Edward T Chouchani, Andrew M James, Alexina C Haynes, W Todd Lowther, Michael P Murphy, Arti Shukla, Nicholas H Heintz

Immunological effects of the TGFβ-blocking antibody GC1008 in malignant pleural mesothelioma patients

TGFβ阻断抗体GC1008对恶性胸膜间皮瘤患者的免疫学影响

Stevenson, James P; Kindler, Hedy L; Papasavvas, Emmanouil; Sun, Jing; Jacobs-Small, Mona; Hull, Jennifer; Schwed, Daniel; Ranganathan, Anjana; Newick, Kheng; Heitjan, Daniel F; Langer, Corey J; McPherson, John M; Montaner, Luis J; Albelda, Steven M

Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells

线粒体靶向硝基氧化物破坏线粒体结构,并抑制恶性间皮瘤细胞中过氧化物酶3和FOXM1的表达。

Cunniff, Brian; Benson, Kira; Stumpff, Jason; Newick, Kheng; Held, Paul; Taatjes, Douglas; Joseph, Joy; Kalyanaraman, Balaraman; Heintz, Nicholas H

Non-specific DNA binding interferes with the efficient excision of oxidative lesions from chromatin by the human DNA glycosylase, NEIL1

非特异性 DNA 结合会干扰人类 DNA 糖基化酶 NEIL1 从染色质中有效切除氧化损伤

Ian D Odell, Kheng Newick, Nicholas H Heintz, Susan S Wallace, David S Pederson