日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intralysosomal pathogens differentially influence the proteolytic potential of their niche

溶酶体内病原体对其微环境的蛋白水解潜力产生不同的影响。

Bird, Lauren E; Xu, Bangyan; Thomas, David R; McGowan, Erin N S; Newton, Patrice; Scott, Nichollas E; McConville, Malcolm J; Edgington-Mitchell, Laura E; Newton, Hayley J

Coxiella burnetii manipulates the lysosomal protease cathepsin B to facilitate intracellular success.

伯氏考克斯体操纵溶酶体蛋白酶组织蛋白酶 B 以促进细胞内感染的成功

Bird Lauren E, Xu Bangyan, Hobbs Andrew D, Ziegler Alexander R, Scott Nichollas E, Newton Patrice, Thomas David R, Edgington-Mitchell Laura E, Newton Hayley J

Legionella effector LpPIP recruits protein phosphatase 1 to the mitochondria to induce dephosphorylation of outer membrane proteins.

军团菌效应蛋白 LpPIP 将蛋白磷酸酶 1 募集到线粒体,诱导外膜蛋白去磷酸化

Yek Kai-Qi, Hodgson Evie R, Ang Ching-Seng, Palmer Catherine S, Frazier Ann E, Newton Hayley J, Stojanovski Diana

The complete genome sequence of the crayfish pathogen Candidatus Paracoxiella cheracis n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family

螯虾病原体 Candidatus Paracoxiella cheracis ngnsp. 的完整基因组序列为了解其致病机制和 Coxiellaceae 科的系统发育提供了重要信息。

Ingle, Danielle J; Walsh, Calum J; Samuel, Genevieve R; Wick, Ryan R; Davidovich, Nadav; Fiocchi, Eleonora; Judd, Louise M; Elliman, Jennifer; Owens, Leigh; Stinear, Timothy P; Basso, Andrea; Pretto, Tobia; Newton, Hayley J

Systematic Discovery of Pathogen Effector Functions across Human Pathogens and Pathways.

系统性地发现人类病原体和通路中的病原效应功能。

Pachano Tomas, Leng He, Dugied Guillaume, Tribble Travis, Loubiere Vincent, Rauh Felix, Lee Yeojin, Schleiffer Alexander, Young Veronika, Weller Benjamin, Lyons Eleanor A, Hass Matthew R, Kottayan Leah C, Weirauch Matthew T, Fuxman Bass Juan I, Newton Hayley J, Ensminger Alexander W, Braun Pascal Falter, Schramek Daniel, Stark Alexander, Taipale Mikko

Genomic epidemiology and phenotypic characterisation of Salmonella enterica serovar Panama in Victoria, Australia

澳大利亚维多利亚州巴拿马沙门氏菌血清型的基因组流行病学和表型特征

Thakur, Samriddhi; Baines, Sarah L; Sia, Cheryll M; Valcanis, Mary; Judd, Louise M; Howden, Benjamin P; Newton, Hayley J; Ingle, Danielle J

A high-throughput cytotoxicity screening platform reveals agr-independent mutations in bacteraemia-associated Staphylococcus aureus that promote intracellular persistence.

高通量细胞毒性筛选平台揭示了与菌血症相关的金黄色葡萄球菌中与agr无关的突变,这些突变促进了细胞内持久性

Hachani Abderrahman, Giulieri Stefano G, Guérillot Romain, Walsh Calum J, Herisse Marion, Soe Ye Mon, Baines Sarah L, Thomas David R, Cheung Shane Doris, Hayes Ashleigh S, Cho Ellie, Newton Hayley J, Pidot Sacha, Massey Ruth C, Howden Benjamin P, Stinear Timothy P

Disruption of Iron Homeostasis and Mitochondrial Metabolism Are Promising Targets to Inhibit Candida auris.

铁稳态和线粒体代谢的破坏是抑制耳念珠菌感染的潜在靶点

Simm Claudia, Weerasinghe Harshini, Thomas David R, Harrison Paul F, Newton Hayley J, Beilharz Traude H, Traven Ana

Interfering with Autophagy: The Opposing Strategies Deployed by Legionella pneumophila and Coxiella burnetii Effector Proteins

干扰自噬:嗜肺军团菌和伯氏考克斯体效应蛋白所采取的相反策略

Thomas, David R; Newton, Patrice; Lau, Nicole; Newton, Hayley J

Dot/Icm-Translocated Proteins Important for Biogenesis of the Coxiella burnetii-Containing Vacuole Identified by Screening of an Effector Mutant Sublibrary.

通过筛选效应突变体亚文库鉴定出对伯氏考克斯体液泡生物发生至关重要的点/Icm转位蛋白

Crabill Emerson, Schofield Whitman B, Newton Hayley J, Goodman Andrew L, Roy Craig R