日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Plasmacytoid dendritic cells in the intestine preferentially produce interferon lambda at homeostasis contributing to tonic localized innate immune responses.

肠道中的浆细胞样树突状细胞在体内平衡状态下优先产生干扰素λ,从而促进持续的局部先天免疫反应

Constant David A, Van Winkle Jacob A, Norwood Philip A, Mishra Gargi, Meyer Kimberly A, Laney Margaret E, Madden Shelby R, Griffith Alec, Rodrigues Patrick Fernandes, Savan Ram, Nice Timothy J

Role of type-I and type-III interferons in gastrointestinal homeostasis and pathogenesis

I型和III型干扰素在胃肠道稳态和发病机制中的作用

Wright, Austin P; Nice, Timothy J

Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium.

肠道菌群的稳态干扰素-λ反应刺激肠道上皮特定区域内的先发制人的抗病毒防御

Van Winkle Jacob A, Peterson Stefan T, Kennedy Elizabeth A, Wheadon Michael J, Ingle Harshad, Desai Chandni, Rodgers Rachel, Constant David A, Wright Austin P, Li Lena, Artyomov Maxim N, Lee Sanghyun, Baldridge Megan T, Nice Timothy J

Interferon Lambda in the Pathogenesis of Inflammatory Bowel Diseases

干扰素λ在炎症性肠病发病机制中的作用

Wallace, Jonathan W; Constant, David A; Nice, Timothy J

Innate immune sensing by epithelial barriers

上皮屏障的先天免疫感知

Constant, David A; Nice, Timothy J; Rauch, Isabella

CD300lf Conditional Knockout Mouse Reveals Strain-Specific Cellular Tropism of Murine Norovirus

CD300lf 条件性敲除小鼠揭示鼠诺如病毒的毒株特异性细胞嗜性

Graziano, Vincent R; Alfajaro, Mia Madel; Schmitz, Cameron O; Filler, Renata B; Strine, Madison S; Wei, Jin; Hsieh, Leon L; Baldridge, Megan T; Nice, Timothy J; Lee, Sanghyun; Orchard, Robert C; Wilen, Craig B

A small RNA is functional in Escherichia fergusonii despite containing a large insertion

尽管含有较大的插入片段,但一种小RNA在弗氏大肠杆菌中仍具有功能。

Wright, Austin P; Dutcher, H Auguste; Butler, Brianna; Nice, Timothy J; Raghavan, Rahul

Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells

半胱天冬酶介导的鼠诺如病毒NS1/2的切割可增强细胞凋亡,并且是肠道上皮细胞持续感染所必需的。

Robinson, Bridget A; Van Winkle, Jacob A; McCune, Broc T; Peters, A Mack; Nice, Timothy J

The Role of Interferon in Persistent Viral Infection: Insights from Murine Norovirus

干扰素在持续性病毒感染中的作用:来自小鼠诺如病毒的启示

Nice, Timothy J; Robinson, Bridget A; Van Winkle, Jacob A

Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity

更正:尽管适应性免疫增强,但树突状细胞中 I 型干扰素受体的缺乏仍会促进小鼠诺如病毒在全身的持续存在。

Nice, Timothy J; Osborne, Lisa C; Tomov, Vesselin T; Artis, David; Wherry, E John; Virgin, Herbert W