Nichol Kristy相关文献与解析，生知库 | 链接生命科学的每一步

Bile acids in the lower airways is associated with airway microbiota changes in chronic obstructive pulmonary disease: an observational study

下呼吸道胆汁酸与慢性阻塞性肺疾病患者气道微生物群变化相关：一项观察性研究

doi:10.1136/bmjresp-2024-002552

Caparros-Martin, Jose A; Saladié, Montserrat; Agudelo-Romero, S Patricia; Nichol, Kristy S; Reen, F Jerry; Moodley, Yuben P; Mulrennan, Siobhain; Stick, Stephen; Wark, Peter A B; O'Gara, Fergal

Severe asthma ILC2s demonstrate enhanced proliferation that is modified by biologics

重度哮喘患者的ILC2细胞增殖增强，而生物制剂可以调节这种增殖。

期刊:Respirology

影响因子:6.3

doi:10.1111/resp.14506

Malik, Bilal; Bartlett, Nathan W; Upham, John W; Nichol, Kristy S; Harrington, John; Wark, Peter A B

Mechanical forces suppress antiviral innate immune responses from asthmatic airway epithelial cells following rhinovirus infection

机械力会抑制鼻病毒感染后哮喘气道上皮细胞的抗病毒先天免疫反应。

期刊:American Journal of Physiology-Lung Cellular and Molecular Physiology

影响因子:3.5

doi:10.1152/ajplung.00074.2022

Veerati, Punnam Chander; Reid, Andrew T; Nichol, Kristy S; Wark, Peter A B; Knight, Darryl A; Bartlett, Nathan W; Grainge, Christopher L

The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi

利用慢性阻塞性肺病类器官研究宿主-病原体相互作用揭示了SARS-CoV-2在支气管中增强的病毒适应性

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-022-35253-x

Chan, Louisa L Y; Anderson, Danielle E; Cheng, Hong Sheng; Ivan, Fransiskus Xaverius; Chen, Si; Kang, Adrian E Z; Foo, Randy; Gamage, Akshamal M; Tiew, Pei Yee; Koh, Mariko Siyue; Lee, Ken Cheah Hooi; Nichol, Kristy; Pathinayake, Prabuddha S; Chan, Yik Lung; Yeo, Tsin Wen; Oliver, Brian G; Wark, Peter A B; Liu, Linbo; Tan, Nguan Soon; Wang, Lin-Fa; Chotirmall, Sanjay H

The Effects of Increasing Fruit and Vegetable Intake in Children with Asthma on the Modulation of Innate Immune Responses.

增加哮喘儿童水果和蔬菜摄入量对调节先天免疫反应的影响

期刊:Nutrients

影响因子:5

doi:10.3390/nu14153087

Hosseini Banafsheh, Berthon Bronwyn S, Jensen Megan E, McLoughlin Rebecca F, Wark Peter A B, Nichol Kristy, Williams Evan J, Baines Katherine J, Collison Adam, Starkey Malcolm R, Mattes Joerg, Wood Lisa G

ACE2 expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma

ACE2在老年人和健康男性的气道上皮细胞中表达升高，但在哮喘患者中表达降低。

期刊:Respirology

影响因子:6.3

doi:10.1111/resp.14003

Wark, Peter A B; Pathinayake, Prabuddha S; Kaiko, Gerard; Nichol, Kristy; Ali, Ayesha; Chen, Ling; Sutanto, Erika N; Garratt, Luke W; Sohal, Sukhwinder S; Lu, Wenying; Eapen, Mathew S; Oldmeadow, Christopher; Bartlett, Nathan; Reid, Andrew; Veerati, Punnam; Hsu, Alan C-Y; Looi, Kevin; Iosifidis, Thomas; Stick, Stephen M; Hansbro, Philip M; Kicic, Anthony

Children With Asthma Have Impaired Innate Immunity and Increased Numbers of Type 2 Innate Lymphoid Cells Compared With Healthy Controls.

与健康对照组相比，哮喘患儿的先天免疫力受损，2 型先天淋巴细胞数量增加

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2021.664668

Hosseini Banafshe, Berthon Bronwyn S, Starkey Malcolm R, Collison Adam, McLoughlin Rebecca F, Williams Evan J, Nichol Kristy, Wark Peter Ab, Jensen Megan E, Da Silva Sena Carla Rebeca, Baines Katherine J, Mattes Joerg, Wood Lisa G

MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD

microRNA-125a 和 -b 抑制 A20 和 MAVS，从而促进 COPD 中的炎症并损害抗病毒反应。

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.90443

Hsu, Alan C-Y; Dua, Kamal; Starkey, Malcolm R; Haw, Tatt-Jhong; Nair, Prema M; Nichol, Kristy; Zammit, Nathan; Grey, Shane T; Baines, Katherine J; Foster, Paul S; Hansbro, Philip M; Wark, Peter A

Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells

人呼吸道上皮细胞中黄嘌呤脱氢酶基因表达和尿酸生成的调控

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0184260

Huff, Ryan D; Hsu, Alan C-Y; Nichol, Kristy S; Jones, Bernadette; Knight, Darryl A; Wark, Peter A B; Hansbro, Philip M; Hirota, Jeremy A

Endoplasmic reticulum stress enhances the expression of TLR3-induced TSLP by airway epithelium

内质网应激增强气道上皮细胞中TLR3诱导的TSLP的表达。

Bile acids in the lower airways is associated with airway microbiota changes in chronic obstructive pulmonary disease: an observational study

下呼吸道胆汁酸与慢性阻塞性肺疾病患者气道微生物群变化相关：一项观察性研究

Severe asthma ILC2s demonstrate enhanced proliferation that is modified by biologics

重度哮喘患者的ILC2细胞增殖增强，而生物制剂可以调节这种增殖。

Mechanical forces suppress antiviral innate immune responses from asthmatic airway epithelial cells following rhinovirus infection

机械力会抑制鼻病毒感染后哮喘气道上皮细胞的抗病毒先天免疫反应。

The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi

利用慢性阻塞性肺病类器官研究宿主-病原体相互作用揭示了SARS-CoV-2在支气管中增强的病毒适应性

The Effects of Increasing Fruit and Vegetable Intake in Children with Asthma on the Modulation of Innate Immune Responses.

增加哮喘儿童水果和蔬菜摄入量对调节先天免疫反应的影响

ACE2 expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma

ACE2在老年人和健康男性的气道上皮细胞中表达升高，但在哮喘患者中表达降低。

Children With Asthma Have Impaired Innate Immunity and Increased Numbers of Type 2 Innate Lymphoid Cells Compared With Healthy Controls.

与健康对照组相比，哮喘患儿的先天免疫力受损，2 型先天淋巴细胞数量增加

MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD

microRNA-125a 和 -b 抑制 A20 和 MAVS，从而促进 COPD 中的炎症并损害抗病毒反应。

Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells

人呼吸道上皮细胞中黄嘌呤脱氢酶基因表达和尿酸生成的调控