Nicholas J Gay相关文献与解析，生知库 | 链接生命科学的每一步

Yoann Saucereau, Thomas H Wilson, Matthew C K Tang, Martin C Moncrieffe, Steven W Hardwick, Dimitri Y Chirgadze, Sandro G Soares, Maria Jose Marcaida, Nicholas J Gay, Monique Gangloff

免疫

发表日期：2022

文献求助收藏

Activation of Toll-like receptor 4 by Ebola virus-shed glycoprotein is direct and requires the internal fusion loop but not glycosylation

埃博拉病毒脱落糖蛋白直接激活 Toll 样受体 4，需要内部融合环，而不是糖基化

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2022.111562

Michael J Scherm, Monique Gangloff, Nicholas J Gay

MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling

MyD88 死亡结构域寡聚化决定肌小体结构：对 Toll 样受体信号传导的影响

期刊:Structure

影响因子:4.4

doi:10.1016/j.str.2020.01.003

Martin C Moncrieffe, Daniel Bollschweiler, Bing Li, Pawel A Penczek, Lee Hopkins, Clare E Bryant, David Klenerman, Nicholas J Gay

The Parkinson's disease-associated kinase LRRK2 regulates genes required for cell adhesion, polarization, and chemotaxis in activated murine macrophages

帕金森病相关激酶 LRRK2 调节活化小鼠巨噬细胞中细胞粘附、极化和趋化所需的基因

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.RA119.011842

Daniel R Levy, Atul Udgata, Panagiotis Tourlomousis, Martyn F Symmons, Lee J Hopkins, Clare E Bryant, Nicholas J Gay

Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain

BCAP 对 TLR 信号传导的负向调控需要其 DBB 结构域的二聚化

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.1901210

Johannes U Lauenstein, Michael J Scherm, Atul Udgata, Martin C Moncrieffe, David I Fisher, Nicholas J Gay

信号转导

发表日期：2020

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Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4

酰基链饱和将心磷脂从拮抗剂转化为 Toll 样受体 4 的激活剂

期刊:Cellular and Molecular Life Sciences

影响因子:6.2

doi:10.1007/s00018-019-03113-5

Malvina Pizzuto, Caroline Lonez, Alberto Baroja-Mazo, Helios Martínez-Banaclocha, Panagiotis Tourlomousis, Monique Gangloff, Pablo Pelegrin, Jean-Marie Ruysschaert, Nicholas J Gay, Clare E Bryant

The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming

弓形虫微线体蛋白 1 和 4 的凝集素特异性活性与 Toll 样受体 2 和 4 N-聚糖结合，以调节先天免疫启动

期刊:PLoS Pathogens

影响因子:5.5

doi:10.1371/journal.ppat.1007871

Aline Sardinha-Silva, Flávia C Mendonça-Natividade, Camila F Pinzan, Carla D Lopes, Diego L Costa, Damien Jacot, Fabricio F Fernandes, André L V Zorzetto-Fernandes, Nicholas J Gay, Alan Sher, Dragana Jankovic, Dominique Soldati-Favre, Michael E Grigg, Maria Cristina Roque-Barreira

Phosphorylation of the multifunctional signal transducer B-cell adaptor protein (BCAP) promotes recruitment of multiple SH2/SH3 proteins including GRB2

多功能信号转导 B 细胞衔接蛋白 (BCAP) 的磷酸化促进多种 SH2/SH3 蛋白的募集，包括 GRB2

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.RA119.009931

Johannes U Lauenstein, Atul Udgata, Alex Bartram, Delphine De Sutter, David I Fisher, Samer Halabi, Sven Eyckerman, Nicholas J Gay

Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells

转化和原代人类免疫细胞中 Polo 样激酶 (PLK) 和 Toll 样受体 (TLR) 信号传导之间的推定联系

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-019-49017-z

Souhayla El Maadidi, Alexander N R Weber, Precious Motshwene, Jan Moritz Schüssler, Daniel Backes, Sabine Dickhöfer, Hui Wang, Xiao Liu, Magno Delmiro Garcia, Christoph Taumer, Boumediene Soufi, Olaf-Oliver Wolz, Sascha N Klimosch, Mirita Franz-Wachtel, Boris Macek, Nicholas J Gay

Anterograde trafficking of Toll-like receptors requires the cargo sorting adaptors TMED-2 and 7

Toll 样受体的顺向运输需要货物分拣适配器 TMED-2 和 7

Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti

埃及伊蚊 Toll 免疫受体激活的结构和动力学

Activation of Toll-like receptor 4 by Ebola virus-shed glycoprotein is direct and requires the internal fusion loop but not glycosylation

埃博拉病毒脱落糖蛋白直接激活 Toll 样受体 4，需要内部融合环，而不是糖基化

MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling

MyD88 死亡结构域寡聚化决定肌小体结构：对 Toll 样受体信号传导的影响

The Parkinson's disease-associated kinase LRRK2 regulates genes required for cell adhesion, polarization, and chemotaxis in activated murine macrophages

帕金森病相关激酶 LRRK2 调节活化小鼠巨噬细胞中细胞粘附、极化和趋化所需的基因

Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain

BCAP 对 TLR 信号传导的负向调控需要其 DBB 结构域的二聚化

Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4

酰基链饱和将心磷脂从拮抗剂转化为 Toll 样受体 4 的激活剂

The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming

弓形虫微线体蛋白 1 和 4 的凝集素特异性活性与 Toll 样受体 2 和 4 N-聚糖结合，以调节先天免疫启动

Phosphorylation of the multifunctional signal transducer B-cell adaptor protein (BCAP) promotes recruitment of multiple SH2/SH3 proteins including GRB2

多功能信号转导 B 细胞衔接蛋白 (BCAP) 的磷酸化促进多种 SH2/SH3 蛋白的募集，包括 GRB2

Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells

转化和原代人类免疫细胞中 Polo 样激酶 (PLK) 和 Toll 样受体 (TLR) 信号传导之间的推定联系