日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Down-Regulation of ABCA7 in Human Microglia, Astrocyte and THP-1 Cell Lines by Cholesterol Depletion, IL-1β and TNFα, or PMA

胆固醇耗竭、IL-1β 和 TNFα 或 PMA 导致人类小胶质细胞、星形胶质细胞和 THP-1 细胞系中的 ABCA7 下调

Joel P Wiener, Sindy Desire, Viktor Garliyev, Nicholas Lyssenko Iii, Domenico Praticò, Nicholas N Lyssenko

ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease

ApoJ/簇蛋白浓度是脑脊液胆固醇外流能力的决定因素,其水平降低与阿尔茨海默病相关。

Yi-An Ko # ,Jeffrey T Billheimer # ,Nicholas N Lyssenko ,Alexandra Kueider-Paisley ,David A Wolk ,Steven E Arnold ,Yuk Yee Leung ,Leslie M Shaw ,John Q Trojanowski ,Rima F Kaddurah-Daouk ,Mitchel A Kling ,Daniel J Rader

Specificity of ABCA7-mediated cell lipid efflux

ABCA7 介导的细胞脂质外排的特异性

Antonino Picataggi, Amrith Rodrigues, Debra A Cromley, Hu Wang, Joel P Wiener, Viktor Garliyev, Jeffrey T Billheimer, Brian C Grabiner, Jessica A Hurt, Allen C Chen, Xianlin Han, Daniel J Rader, Domenico Praticò, Nicholas N Lyssenko

ABCA7 and the altered lipidostasis hypothesis of Alzheimer's disease

ABCA7 与阿尔茨海默病脂质稳态改变假说

Nicholas N Lyssenko, Domenico Praticò

Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease

神经细胞脑脊液胆固醇流出能力的相关性和预测因素,阿尔茨海默病胆固醇流行病学的生物标志物家族

Eleonora Cipollari, Hannah J Szapary, Antonino Picataggi, Jeffrey T Billheimer, Catherine A Lyssenko, Gui-Shuang Ying, Leslie M Shaw, Mitchel A Kling, Rima Kaddurah-Daouk, Daniel J Rader, Domenico Praticò, Nicholas N Lyssenko; Alzheimer’s Disease Metabolomics Consortium

Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics

开发新型 DNA 编码 PCSK9 单克隆抗体作为降脂疗法

Makan Khoshnejad, Ami Patel, Krzysztof Wojtak, Sagar B Kudchodkar, Laurent Humeau, Nicholas N Lyssenko, Daniel J Rader, Kar Muthumani, David B Weiner

Directional ABCA1-mediated cholesterol efflux and apoB-lipoprotein secretion in the retinal pigment epithelium

视网膜色素上皮中定向 ABCA1 介导的胆固醇外流和载脂蛋白 B 脂蛋白的分泌

Nicholas N Lyssenko, Naqi Haider, Antonino Picataggi, Eleonora Cipollari, Wanzhen Jiao, Michael C Phillips, Daniel J Rader, Venkata Ramana Murthy Chavali

ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion

人诱导多能干细胞来源的肝细胞中ATP结合盒转运蛋白A1的缺乏会抑制高密度脂蛋白的生物合成并增强甘油三酯的分泌。

Xin Bi ,Evanthia E Pashos ,Marina Cuchel ,Nicholas N Lyssenko ,Mayda Hernandez ,Antonino Picataggi ,James McParland ,Wenli Yang ,Ying Liu ,Ruilan Yan ,Christopher Yu ,Stephanie L DerOhannessian ,Michael C Phillips ,Edward E Morrisey ,Stephen A Duncan ,Daniel J Rader

Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein

细胞胆固醇向高密度脂蛋白的设计功能模拟物进行强劲的被动和主动流出

Andrea J Luthi, Nicholas N Lyssenko, Duyen Quach, Kaylin M McMahon, John S Millar, Kasey C Vickers, Daniel J Rader, Michael C Phillips, Chad A Mirkin, C Shad Thaxton

Factors controlling nascent high-density lipoprotein particle heterogeneity: ATP-binding cassette transporter A1 activity and cell lipid and apolipoprotein AI availability

控制新生高密度脂蛋白颗粒异质性的因素:ATP 结合盒转运蛋白 A1 活性以及细胞脂质和载脂蛋白 AI 的可用性

Nicholas N Lyssenko, Margaret Nickel, Chongren Tang, Michael C Phillips