日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Paradoxical Maturity-Onset Diabetes of the Young Arising From Loss-of-Function Mutations in ATP-Sensitive Potassium Channels

由ATP敏感钾通道功能丧失突变引起的矛盾性青年糖尿病

Scala, Rosa; Li, Yunpeng; Gao, Jian; York, Nathan W; Unnikrishnan, Ranjit; Anjana, Ranjit Mohan; Mohan, Viswanathan; Sundaramoorthy, Gopi; Kavitha, Babu; Radha, Venkatesan; Nichols, Colin G

Cantu syndrome-associated SUR2[H60Y] mutation confers selective gain of function on Kir6.1 ATP-sensitive potassium channels

Cantu综合征相关的SUR2[H60Y]突变赋予Kir6.1 ATP敏感性钾通道选择性功能获得。

Gao, Jian; Thompson, Ellen T; Nichols, Colin G

Loss of β-Cell KATP Reduces Ca2+ Sensitivity of Insulin Secretion and Trpm5 Expression

β细胞KATP的缺失会降低胰岛素分泌对Ca2+的敏感性并影响Trpm5的表达。

York, Nathaniel W; Yan, Zihan; Osipovich, Anna B; Tate, Abbie; Patel, Sumit; Piston, David W; Magnuson, Mark A; Remedi, Maria S; Nichols, Colin G

Molecular basis of TRPV3 channel blockade by intracellular polyamines

细胞内多胺阻断TRPV3通道的分子基础

Zhang, Jingying; Yuan, Peng; Nichols, Colin G; Maksaev, Grigory

Control of neurovascular coupling by ATP-sensitive potassium channels

ATP敏感性钾通道对神经血管耦合的调控

Bowen, Ryan M; York, Nathaniel W; Padawer-Curry, Jonah; Bauer, Adam Q; Lee, Jin-Moo; Nichols, Colin G

Bayliss-Starling Prize Lecture: K(ATP) channel pathophysiology - a whole-body odyssey

贝利斯-斯塔林奖讲座:K(ATP)通道病理生理学——全身之旅

Nichols, Colin G

Treatment of overactive K(ATP) channels with glibenclamide in a zebrafish model and a clinical trial in humans with Cantú syndrome

在斑马鱼模型中用格列本脲治疗过度活跃的K(ATP)通道,以及在患有坎图综合征的人类中进行临床试验

Kleinendorst, Lotte; Siegelaar, Sarah E; Roessler, Helen I; Meiwand, Lema; van den Boogaard, Malou; de Bruin-Bon, Rianne H A C M; van Duinen, Kirsten F; Planken, R Nils; Jaspars, Elisabeth H; Kemperman, Patrick M J H; Bouma, Berto J; Nichols, Colin G; Bekkenk, Marcel W; van Haaften, Gijs W; van Haelst, Mieke M

Dynein light chains 1 and 2 are auxiliary proteins of pH-sensitive Kir4.1 channels.

动力蛋白轻链 1 和 2 是 pH 敏感 Kir4.1 通道的辅助蛋白

Lee Sun-Joo, Gao Jian, Thompson Ellen, Mount Jonathan, Nichols Colin G

From Selective Permeation to Physiology in Potassium Channels

从选择性渗透到钾通道的生理学

Lee, Sun-Joo; Schillings, Johanna; de Vries, Reinier; Matamoros, Marcos; de Groot, Bert L; Nichols, Colin G

Gain-of-function mutations in KATP channel subunits compromise colonic tight junction integrity and epithelial homeostasis in murine models of Cantú syndrome.

在坎图综合征小鼠模型中,KATP 通道亚基的功能获得性突变会损害结肠紧密连接的完整性和上皮稳态。

Maqoud Fatima, Mallardi Domenica, Orlando Antonella, Tricarico Domenico, Nichols Colin G, Antonacci Marina, Bianco Giusy, Armentano Raffaele, Grassi Ilaria, Valentini Anna Maria, Russo Francesco