日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multiple intramolecular triggers converge to preferential G protein coupling in the CB(2)R

多种分子内触发因素汇聚于CB(2)受体中G蛋白的优先偶联。

Morales-Pastor, Adrian; Miljuš, Tamara; Dieguez-Eceolaza, Miguel; Stępniewski, Tomasz Maciej; Ledesma-Martin, Vicente; Heydenreich, Franziska M; Flock, Tilman; Plouffe, Bianca; Le Gouill, Christian; Duchaine, Jean; Sykes, David A; Nicholson, Colin; Koers, Eline J; Guba, Wolfgang; Rufer, Arne C; Grether, Uwe; Bouvier, Michel; Veprintsev, Dmitry B; Selent, Jana

Agonist efficacy at the β(2)AR is driven by the faster association rate of the G(s) protein.

β(2)AR 激动剂的效力取决于 G(s) 蛋白结合速率的加快

Harwood Clare R, Sykes David A, Redfern-Nichols Theo, Underwood Owen, Nicholson Colin, Khoshgrudi Armin N, Koers Eline J, Ladds Graham, Briddon Stephen J, Veprintsev Dmitry B