Cardiac NAD(+) depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics
小鼠心脏中 NAD(+) 耗竭会促进肥厚型心肌病和心律失常,随后才会出现生物能量学障碍。
期刊:Nature Cardiovascular Research
影响因子:
doi:10.1038/s44161-024-00542-9
Doan, Khanh V; Luongo, Timothy S; Ts'olo, Thato T; Lee, Won Dong; Frederick, David W; Mukherjee, Sarmistha; Adzika, Gabriel K; Perry, Caroline E; Gaspar, Ryan B; Walker, Nicole; Blair, Megan C; Bye, Nicole; Davis, James G; Holman, Corey D; Chu, Qingwei; Wang, Lin; Rabinowitz, Joshua D; Kelly, Daniel P; Cappola, Thomas P; Margulies, Kenneth B; Baur, Joseph A