日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

In Vivo Studies of [(161)Tb]Tb-Trastuzumab Radiopharmaceutical Therapy in Human Epidermal Growth Factor Receptor 2-Expressing Breast Tumors Show High Tumor Uptake and Tumor Growth Suppression

在表达人表皮生长因子受体2的乳腺肿瘤中，[(161)Tb]Tb-曲妥珠单抗放射性药物治疗的体内研究显示，肿瘤摄取率高，且能抑制肿瘤生长。

期刊:
影响因子:
doi:10.2967/jnumed.125.269741
Cold, Sigrid; Sadasivam, Pragalath; Wessel, Mette M; Ischyropoulou, Myrto; Fonslet, Jesper; Engel, Trine B; Nielsen, Carsten H; Kjaer, Andreas; Kristensen, Lotte K
信号转导
Human
肿瘤
肿瘤免疫
发表日期：2026
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A Targeted Thorium-227 Conjugate Demonstrates Efficacy in Preclinical Models of Acquired Drug Resistance and Combination Potential with Chemotherapeutics and Antiangiogenic Therapies.

靶向钍-227偶联物在获得性耐药的临床前模型中显示出疗效，并具有与化疗药物和抗血管生成疗法联合应用的潜力

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-22-0808
Zitzmann-Kolbe Sabine, Kristian Alexander, Zopf Dieter, Kamfenkel Claudia, Politz Oliver, Ellingsen Christine, Hilbig Jochen, Juul Mark U, Fonslet Jesper, Nielsen Carsten H, Schatz Christoph A, Bjerke Roger M, Cuthbertson Alan S, Mumberg Dominik, Hagemann Urs B
心血管
血管生成
发表日期：2023
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Immunostimulatory effects of targeted thorium-227 conjugates as single agent and in combination with anti-PD-L1 therapy

靶向钍-227偶联物作为单药及与抗PD-L1疗法联合应用时的免疫刺激作用

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2021-002387
Lejeune, Pascale; Cruciani, Véronique; Berg-Larsen, Axel; Schlicker, Andreas; Mobergslien, Anne; Bartnitzky, Lisa; Berndt, Sandra; Zitzmann-Kolbe, Sabine; Kamfenkel, Claudia; Stargard, Stefan; Hammer, Stefanie; Jørgensen, Jennifer S; Jackerott, Malene; Nielsen, Carsten H; Schatz, Christoph A; Hennekes, Hartwig; Karlsson, Jenny; Cuthbertson, Alan S; Mumberg, Dominik; Hagemann, Urs B
PD-L1
免疫/内分泌
发表日期：2021
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A blood biomarker for monitoring response to anti-EGFR therapy.

用于监测抗 EGFR 疗法疗效的血液生物标志物。

期刊:Cancer Biomarkers
影响因子:1.9
doi:10.3233/CBM-171149
Hughes Nicholas P, Xu Lingyun, Nielsen Carsten H, Chang Edwin, Hori Sharon S, Natarajan Arutselvan, Lee Samantha, Kjær Andreas, Kani Kian, Wang Shan X, Mallick Parag, Gambhir Sanjiv Sam
EGF
EGFR
发表日期：2018
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Neodymium-140 DOTA-LM3: Evaluation of an In Vivo Generator for PET with a Non-Internalizing Vector

钕-140 DOTA-LM3：一种用于PET的非内化载体的体内发生器的评估

期刊:Frontiers in Medicine
影响因子:3
doi:10.3389/fmed.2017.00098
Severin, Gregory W; Kristensen, Lotte K; Nielsen, Carsten H; Fonslet, Jesper; Jensen, Andreas I; Frellsen, Anders F; Jensen, K M; Elema, Dennis R; Maecke, Helmut; Kjær, Andreas; Johnston, Karl; Köster, Ulli
发表日期：2017
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First-in-human uPAR PET: Imaging of Cancer Aggressiveness

首次人体uPAR PET：癌症侵袭性的成像

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.12956
Persson, Morten; Skovgaard, Dorthe; Brandt-Larsen, Malene; Christensen, Camilla; Madsen, Jacob; Nielsen, Carsten H; Thurison, Tine; Klausen, Thomas Levin; Holm, Søren; Loft, Annika; Berthelsen, Anne Kiil; Ploug, Michael; Pappot, Helle; Brasso, Klaus; Kroman, Niels; Højgaard, Liselotte; Kjaer, Andreas
uPAR
肿瘤
uPA
肿瘤免疫
发表日期：2015
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A titratable two-step transcriptional amplification strategy for targeted gene therapy based on ligand-induced intramolecular folding of a mutant human estrogen receptor

一种基于配体诱导的突变型人雌激素受体分子内折叠的可滴定两步转录扩增策略，用于靶向基因治疗

期刊:Molecular Imaging and Biology
影响因子:2.5
doi:10.1007/s11307-013-0673-4
Chen, Ian Y; Paulmurugan, Ramasamy; Nielsen, Carsten H; Wang, David S; Chow, Vinca; Robbins, Robert C; Gambhir, Sanjiv S
信号转导
基因治疗
免疫/内分泌
发表日期：2014
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Evaluation of σ-1 receptor radioligand 18F-FTC-146 in rats and squirrel monkeys using PET

利用PET对大鼠和松鼠猴体内σ-1受体放射性配体18F-FTC-146进行评价

期刊:
影响因子:
doi:10.2967/jnumed.113.120261
James, Michelle L; Shen, Bin; Nielsen, Carsten H; Behera, Deepak; Buckmaster, Christine L; Mesangeau, Christophe; Zavaleta, Cristina; Vuppala, Pradeep K; Jamalapuram, Seshulatha; Avery, Bonnie A; Lyons, David M; McCurdy, Christopher R; Biswal, Sandip; Gambhir, Sanjiv S; Chin, Frederick T
信号转导
Rat
发表日期：2014
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New positron emission tomography (PET) radioligand for imaging σ-1 receptors in living subjects

一种用于活体受试者体内σ-1受体成像的新型正电子发射断层扫描（PET）放射性配体

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm300371c
James, Michelle L; Shen, Bin; Zavaleta, Cristina L; Nielsen, Carsten H; Mesangeau, Christophe; Vuppala, Pradeep K; Chan, Carmel; Avery, Bonnie A; Fishback, James A; Matsumoto, Rae R; Gambhir, Sanjiv S; McCurdy, Christopher R; Chin, Frederick T
信号转导
发表日期：2012
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Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis

Twist1抑制衰老程序，从而加速并维持突变Kras诱导的肺肿瘤发生。

期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.1002650
Tran, Phuoc T; Shroff, Emelyn H; Burns, Timothy F; Thiyagarajan, Saravanan; Das, Sandhya T; Zabuawala, Tahera; Chen, Joy; Cho, Yoon-Jae; Luong, Richard; Tamayo, Pablo; Salih, Tarek; Aziz, Khaled; Adam, Stacey J; Vicent, Silvestre; Nielsen, Carsten H; Withofs, Nadia; Sweet-Cordero, Alejandro; Gambhir, Sanjiv S; Rudin, Charles M; Felsher, Dean W
肿瘤
衰老
肿瘤免疫
发表日期：2012
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