日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Optical control of the cardiac rhythm with photoswitchable Na(V)1.5 channel blockers

利用光开关型Na(V)1.5通道阻滞剂对心律进行光学控制

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-70305-6
Liu, Shiqi; Guan, Weiqiang; Li, Zhangqiang; Wang, Wei; Song, Huifang; Li, Jia'ao; Hou, Junjie; Wang, Huan; Xiong, JingWei; Yang, Min; Yan, Nieng; Tian, Xin; Li, Houhua; Huang, Zhuo
发表日期：2026
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Absolute hand determination of glycofibrils from natural sources in cryo-EM

利用冷冻电镜对天然来源的糖纤维进行绝对手工测定

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2531477123
Zhang, Qi; Qin, Lanju; Wang, Tongtong; Li, Zhangqiang; Zhang, Yilin; Chen, Sheng; Ge, Qijun; Wen, Jialing; Yan, Nieng; Wang, Jiawei; Hu, Mingxu
发表日期：2026
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Phrixotoxin-3 binds to three distinct antagonistic sites on human Na(v)1.6

Phrixotoxin-3 与人 Na(v)1.6 上的三个不同的拮抗位点结合。

期刊:Cell Research
影响因子:25.9
doi:10.1038/s41422-025-01141-4
Fan, Xiao; Chen, Jiaofeng; Huang, Xiaoshuang; Hou, Zhanfeng; Xie, Yuzhen; Li, Zigang; Yan, Nieng; Huang, Jian
发表日期：2025
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CryoPROS: Correcting misalignment caused by preferred orientation using AI-generated auxiliary particles

CryoPROS：利用人工智能生成的辅助粒子校正由优选取向引起的错位

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-59797-w
Zhang, Hui; Zheng, Dihan; Wu, Qiurong; Yan, Nieng; Peng, Han; Hu, Qi; Peng, Ying; Yan, Zhaofeng; Shi, Zuoqiang; Bao, Chenglong; Hu, Mingxu
发表日期：2025
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Critical role of extracellular loops in differential modulations of TTX-sensitive and TTX-resistant Na(v) channels

细胞外环在TTX敏感型和TTX耐受型Na(v)通道差异性调节中的关键作用

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2510355122
Wu, Tong; Yang, Xinyu; Jin, Xueqin; Yan, Nieng; Li, Zhangqiang
细胞生物学
发表日期：2025
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CryoSeek II: Cryo-EM analysis of glycofibrils from freshwater reveals well-structured glycans coating linear tetrapeptide repeats

CryoSeek II：对淡水中糖原纤维的冷冻电镜分析揭示了结构良好的聚糖包裹着线性四肽重复序列

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2423943122
Wang, Tongtong; Huang, Wenze; Xu, Kui; Sun, Yitong; Zhang, Qiangfeng Cliff; Yan, Chuangye; Li, Zhangqiang; Yan, Nieng
发表日期：2025
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Deciphering Ca(2+) permeation and valence selectivity in Ca(V)1: Molecular dynamics simulations reveal the three-ion knock-on mechanism.

解析 Ca(V)1 中 Ca(2+) 的渗透和价态选择性：分子动力学模拟揭示了三离子碰撞机制

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2424694122
Xue Lingfeng, Yan Nieng, Song Chen
发表日期：2025
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Direct effects of the small molecule PD‑L1 inhibitor BMS‑202 on A375 melanoma cells: Anti‑tumor activity accompanied by increased mitochondrial function.

小分子 PD-L1 抑制剂 BMS-202 对 A375 黑色素瘤细胞的直接作用：抗肿瘤活性伴随线粒体功能增强

期刊:Molecular Medicine Reports
影响因子:3.5
doi:10.3892/mmr.2025.13607
Zhang Nieng, Feng Fenglan, Dang Ruonan, Zhao Xiaoqing, Wang Xingrong, Yang Yuqi, Deng Jinjin, Wang Yujie, Wen Zhuofan, Meng Wei, Huang Xinglan, Zhang Shunying, Deng Yuqiong, Huang Caifeng, Yan Peng, Liu Zhongrong, Cheng Xiping
细胞生物学
肿瘤
黑色素瘤
线粒体
发表日期：2025
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Sensory neuron sodium channels as pain targets; from cocaine to Journavx (VX-548, suzetrigine).

感觉神经元钠通道作为疼痛靶点；从可卡因到 Journavx（VX-548，苏泽曲嗪）

期刊:Journal of General Physiology
影响因子:2.9
doi:10.1085/jgp.202513778
Wood John N, Yan Nieng, Huang Jian, Zhao Jing, Akopian Armen, Cox James J, Woods C Geoffrey, Nassar Mohammed A
神经科学
发表日期：2025
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Structural basis for human Cav3.2 inhibition by selective antagonists

选择性拮抗剂抑制人类 Cav3.2 的结构基础

期刊:Cellular Signalling
影响因子:28.1
doi:10.1038/s41422-024-00959-8
Jian Huang #, Xiao Fan #, Xueqin Jin #, Chen Lyu, Qinmeng Guo, Tao Liu, Jiaofeng Chen, Amaël Davakan, Philippe Lory, Nieng Yan
发表日期：2024
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