日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

KAT6B overexpression in mice causes aggression, anxiety, and epilepsy

小鼠中 KAT6B 过度表达导致攻击性、焦虑和癫痫

Maria I Bergamasco, Ezgi Ozturk, Pablo M Casillas-Espinosa, Alexandra L Garnham, Waruni Abeysekera, Verena C Wimmer, Pradeep Rajasekhar, Hannah K Vanyai, Lachlan Whitehead, Marnie E Blewitt, Kelly Rogers, Adam P Vogel, Anthony J Hannan, Gordon K Smyth, Nigel C Jones, Tim Thomas, Anne K Voss

Tau Phosphorylation Patterns in the Rat Cerebral Cortex After Traumatic Brain Injury and Sodium Selenate Effects: An Epibios4rx Project 2 Study

创伤性脑损伤后大鼠大脑皮层中的 Tau 磷酸化模式和亚硒酸钠的影响:Epibios4rx 项目 2 研究

Patricia Grandizoli Saletti, Pablo M Casillas-Espinosa, Christos Panagiotis Lisgaras, Wenzhu Bi Mowrey, Qianyun Li, Wei Liu, Rhys D Brady, Idrish Ali, Juliana Silva, Glenn Yamakawa, Matt Hudson, Crystal Li, Emma L Braine, Lisa Coles, James C Cloyd, Nigel C Jones, Sandy R Shultz, Solomon L Moshé, Ter

Disease-modifying effects of sodium selenate in a model of drug-resistant, temporal lobe epilepsy

亚硒酸钠对耐药性颞叶癫痫模型的疾病改善作用

Pablo M Casillas-Espinosa, Alison Anderson, Anna Harutyunyan, Crystal Li, Jiyoon Lee, Emma L Braine, Rhys D Brady, Mujun Sun, Cheng Huang, Christopher K Barlow, Anup D Shah, Ralf B Schittenhelm, Richelle Mychasiuk, Nigel C Jones, Sandy R Shultz, Terence J O'Brien

The sulfonadyns: a class of aryl sulfonamides inhibiting dynamin I GTPase and clathrin mediated endocytosis are anti-seizure in animal models

磺胺类药物:一类抑制动力蛋白 I GTPase 和网格蛋白介导的内吞作用的芳基磺胺类药物,在动物模型中具有抗癫痫作用

Luke R Odell, Nigel C Jones, Ngoc Chau, Mark J Robertson, Joseph I Ambrus, Fiona M Deane, Kelly A Young, Ainslie Whiting, Jing Xue, Kate Prichard, James A Daniel, Nick N Gorgani, Terence J O'Brien, Phillip J Robinson, Adam McCluskey

11β-HSD1 participates in epileptogenesis and the associated cognitive impairment by inhibiting apoptosis in mice

11β-HSD1通过抑制小鼠细胞凋亡参与癫痫发生和相关的认知障碍

Xueying Li #, Wanhua Qiu #, Lu Deng, Jingjing Lin, Wenting Huang, Yuchen Xu, Mulan Zhang, Nigel C Jones, Runxuan Lin, Huiqin Xu, Li Lin, Peijun Li, Xinshi Wang

Characterising seizure development, behavioural comorbidities and neuroinflammation in a self-sustained electrical status epilepticus model of mesial temporal lobe epilepsy in C57BL/6J mice

在 C57BL/6J 小鼠的内侧颞叶癫痫自持电状态癫痫持续模型中表征癫痫发作发展、行为合并症和神经炎症

Peravina Thergarajan, Matthew R Hudson, Irena Carmichael, Jérôme Clasadonte, Stefanie Dedeurwaerdere, Terence J O'Brien, Nigel C Jones, Idrish Ali

Differential Effects of Chronic Methamphetamine Treatment on High-Frequency Oscillations and Responses to Acute Methamphetamine and NMDA Receptor Blockade in Conscious Mice

慢性甲基苯丙胺治疗对清醒小鼠高频振荡和对急性甲基苯丙胺和 NMDA 受体阻滞的反应的不同影响

Matthew R Hudson, Joshua Foreman, Gil Rind, Elizabeth E Manning, Nigel C Jones, Maarten van den Buuse

An Integrated Multi-Omic Network Analysis Identifies Seizure-Associated Dysregulated Pathways in the GAERS Model of Absence Epilepsy

综合多组学网络分析确定了失神性癫痫 GAERS 模型中与癫痫发作相关的失调通路

Anna Harutyunyan, Debbie Chong, Rui Li, Anup D Shah, Zahra Ali, Cheng Huang, Christopher K Barlow, Piero Perucca, Terence J O'Brien, Nigel C Jones, Ralf B Schittenhelm, Alison Anderson, Pablo M Casillas-Espinosa

Inhibition of purinergic P2X receptor 7 (P2X7R) decreases granulocyte-macrophage colony-stimulating factor (GM-CSF) expression in U251 glioblastoma cells

抑制嘌呤能 P2X 受体 7 (P2X7R) 可降低 U251 胶质母细胞瘤细胞中的粒细胞-巨噬细胞集落刺激因子 (GM-CSF) 表达

Matthew Drill, Kim L Powell, Liyen Katrina Kan, Nigel C Jones, Terence J O'Brien, John A Hamilton, Mastura Monif

The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states

长链非编码RNA NEAT1对神经元活动有反应,并与过度兴奋状态相关。

Guy Barry,James A Briggs,Do Won Hwang,Sam P Nayler,Patrick R J Fortuna,Nicky Jonkhout,Fabien Dachet,Jesper L V Maag,Pieter Mestdagh,Erin M Singh,Lotta Avesson,Dominik C Kaczorowski,Ezgi Ozturk,Nigel C Jones,Irina Vetter,Luis Arriola-Martinez,Jianfei Hu,Gloria R Franco,Victoria M Warn,Andrew Gong,Marcel E Dinger,Frank Rigo,Leonard Lipovich,Margaret J Morris,Terence J O'Brien,Dong Soo Lee,Jeffrey A Loeb,Seth Blackshaw,John S Mattick,Ernst J Wolvetang