日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Caloric restriction promotes resolution of atherosclerosis in obese mice, while weight regain accelerates its progression

热量限制可促进肥胖小鼠动脉粥样硬化的消退,而体重反弹则会加速其进展。

Scolaro, Bianca; Krautter, Franziska; Brown, Emily J; Guha Ray, Aleepta; Kalev-Altman, Rotem; Petitjean, Marie; Delbare, Sofie; Donahoe, Casey; Pena, Stephanie; Garabedian, Michela L; Nikain, Cyrus A; Laskou, Maria; Tufanli, Ozlem; Hannemann, Carmen; Aouadi, Myriam; Weinstock, Ada; Fisher, Edward A

FITM2 deficiency results in ER lipid accumulation, ER stress, and reduced apolipoprotein B lipidation and VLDL triglyceride secretion in vitro and in mouse liver

FITM2 缺陷会导致内质网脂质积累、内质网应激,并降低载脂蛋白 B 脂化和极低密度脂蛋白甘油三酯分泌,这一现象在体外和鼠肝脏中均有发现。

Wang, Haizhen; Nikain, Cyrus; Fortounas, Konstantinos I; Amengual, Jaume; Tufanli, Ozlem; La Forest, Maxwell; Yu, Yong; Wang, Meng C; Watts, Russell; Lehner, Richard; Qiu, Yunping; Cai, Min; Kurland, Irwin J; Goldberg, Ira J; Rajan, Sujith; Hussain, M Mahmood; Brodsky, Jeffrey L; Fisher, Edward A

γ-Secretase fanning the fire of innate immunity

γ-分泌酶助燃先天免疫之火

Liu, Chenge; Nikain, Cyrus; Li, Yue-Ming

Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression

抑制髓系网蛋白-1可诱导炎症消退和斑块消退

Schlegel, Martin; Sharma, Monika; Brown, Emily J; Newman, Alexandra A C; Cyr, Yannick; Afonso, Milessa Silva; Corr, Emma M; Koelwyn, Graeme J; van Solingen, Coen; Guzman, Jonathan; Farhat, Rubab; Nikain, Cyrus A; Shanley, Lianne C; Peled, Daniel; Schmidt, Ann Marie; Fisher, Edward A; Moore, Kathryn J

Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis

Wnt信号通路增强巨噬细胞对IL-4的反应,并促进动脉粥样硬化的消退。

Ada Weinstock ,Karishma Rahman ,Or Yaacov ,Hitoo Nishi ,Prashanthi Menon ,Cyrus A Nikain ,Michela L Garabedian ,Stephanie Pena ,Naveed Akbar ,Brian E Sansbury ,Sean P Heffron ,Jianhua Liu ,Gregory Marecki ,Dawn Fernandez ,Emily J Brown ,Kelly V Ruggles ,Stephen A Ramsey ,Chiara Giannarelli ,Matthew Spite ,Robin P Choudhury ,P'ng Loke ,Edward A Fisher

Inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in mice

抑制造血细胞中LXRα的磷酸化可减轻炎症,并缓解小鼠的动脉粥样硬化和肥胖。

Maud Voisin ,Elina Shrestha ,Claire Rollet ,Cyrus A Nikain ,Tatjana Josefs ,Mélanie Mahé ,Tessa J Barrett ,Hye Rim Chang ,Rachel Ruoff ,Jeffrey A Schneider ,Michela L Garabedian ,Chris Zoumadakis ,Chi Yun ,Bara Badwan ,Emily J Brown ,Adam C Mar ,Robert J Schneider ,Ira J Goldberg ,Inés Pineda-Torra ,Edward A Fisher ,Michael J Garabedian

Effect of relative social rank within a social hierarchy on neural activation in response to familiar or unfamiliar social signals

社会等级中相对社会地位对熟悉或不熟悉的社会信号引起的神经激活的影响

Lee, Won; Dowd, Hollie N; Nikain, Cyrus; Dwortz, Madeleine F; Yang, Eilene D; Curley, James P

Reshaping of the gastrointestinal microbiome alters atherosclerotic plaque inflammation resolution in mice

重塑胃肠道微生物群可改变小鼠动脉粥样硬化斑块炎症的消退

Garshick, Michael S; Nikain, Cyrus; Tawil, Michael; Pena, Stephanie; Barrett, Tessa J; Wu, Benjamin G; Gao, Zhan; Blaser, Martin J; Fisher, Edward A

Short-Term Acyl-CoA:Cholesterol Acyltransferase Inhibition, Combined with Apoprotein A1 Overexpression, Promotes Atherosclerosis Inflammation Resolution in Mice.

短期酰基辅酶A:胆固醇酰基转移酶抑制,结合载脂蛋白A1过表达,可促进小鼠动脉粥样硬化炎症消退

Amengual Jaume, Ogando Yoscar, Nikain Cyrus, Quezada Alexandra, Qian Kun, Vaisar Tomas, Fisher Edward A

Tamoxifen activity against Plasmodium in vitro and in mice

他莫昔芬在体外和小鼠体内对疟原虫的活性

Weinstock, Ada; Gallego-Delgado, Julio; Gomes, Cláudia; Sherman, Julian; Nikain, Cyrus; Gonzalez, Sandra; Fisher, Edward; Rodriguez, Ana