日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

IRX4204 sensitizes multiple myeloma to ferroptosis and improves lenalidomide efficacy through the HMOX1-GPX4 axis

IRX4204 通过 HMOX1-GPX4 轴增强多发性骨髓瘤对铁死亡的敏感性，并提高来那度胺的疗效。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-42123-9
Wu, Jian; Yan, Zhibo; Burcher, Kimberly; Han, Zhannan; Nikiforov, Mikhail A; Vuligonda, Vidyasagar; Sanders, Martin; Kang, Yubin
铁死亡
多发性骨髓瘤
GPX4
骨髓瘤
发表日期：2026
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The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response

细胞可渗透的铁螯合剂M606通过E2F3介导的反应抑制MYCN驱动的神经母细胞瘤。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2420011122
Pandher, Ruby; Xue, Chengyuan; Gamble, Laura D; Milazzo, Giorgio; Di Giacomo, Simone; Murray, Jayne; Cheung, Leanna; Ferrucci, Francesca; Palombo, Marta; Purgato, Stefania; Burkhart, Catherine A; Fedtsova, Natalia; Gleiberman, Anatoli S; Purmal, Andrei A; Korotchkina, Lioubov; Nikiforov, Mikhail A; Makarov, Sergei S; Telfer, Thomas J; Codd, Rachel; Marshall, Glenn M; Scott, David A; Osterman, Andrei L; Gudkov, Andrei V; Perini, Giovanni; Haber, Michelle; Norris, Murray D
细胞生物学
MYC
发表日期：2025
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Inhibitors of De Novo Guanylate Biosynthesis Enhance the Potency of MAPK Cascade Inhibitors Against Colorectal Cancer

从头鸟苷酸生物合成抑制剂可增强 MAPK 级联抑制剂对结直肠癌的疗效

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms262411959
Maslov, Alexei A; Trageser, Nicholas H; Kichina, Julia V; Elamir, Haya; Gardner, Evelyn; Teaman, Frances; Vishwanath, Vera; Dugas, Scott M; Bianchi-Smiraglia, Anna; Leonova, Katerina I; Gurova, Katerina V; Nikiforov, Mikhail A; Kandel, Eugene S
肿瘤
肠癌
肿瘤免疫
MAPK/ERK
发表日期：2025
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Inhibition of the RAC/PAK Signaling Axis Enhances the Potency of MAPK Cascade Inhibitors Against Uveal Melanoma

抑制 RAC/PAK 信号通路可增强 MAPK 级联抑制剂对葡萄膜黑色素瘤的疗效

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom15101425
Maslov, Alexei A; Trageser, Nicholas H; Kichina, Julia V; Elamir, Haya; Gardner, Evelyn; Teaman, Frances; Vishwanath, Vera; Dugas, Scott M; Heid, Johanna; Maslov, Alexander Y; Withers, Henry G; Bianchi-Smiraglia, Anna; Leonova, Katerina I; Nikiforov, Mikhail A; Kandel, Eugene S
黑色素瘤
信号转导
MAPK/ERK
发表日期：2025
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Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy.

临床药物筛选显示，氯法齐明可增强抗 PD-1 和 CTLA-4 免疫疗法的疗效，同时降低其毒性

期刊:Cancer Cell
影响因子:44.5
doi:10.1016/j.ccell.2024.03.001
Xue Gang, Li Xin, Kalim Muhammad, Fang Jing, Jiang Zhiwu, Zheng Ningbo, Wang Ziyu, Li Xiaoyin, Abdelrahim Maen, He Zhiheng, Nikiforov Mikhail, Jin Guangxu, Lu Yong
其它
药物研究
发表日期：2024
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Compartmentalization and regulation of GTP in control of cellular phenotypes

GTP的区室化和调控在细胞表型控制中的作用

期刊:Trends in Molecular Medicine
影响因子:13.8
doi:10.1016/j.molmed.2022.05.012
Wolff, David W; Bianchi-Smiraglia, Anna; Nikiforov, Mikhail A
信号转导
细胞生物学
发表日期：2022
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Author Correction: Regulation of local GTP availability controls RAC1 activity and cell invasion

作者更正：局部 GTP 可用性的调控控制 RAC1 活性和细胞侵袭

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-021-26665-2
Bianchi-Smiraglia, Anna; Wolff, David W; Marston, Daniel J; Deng, Zhiyong; Han, Zhannan; Moparthy, Sudha; Wombacher, Rebecca M; Mussell, Ashley L; Shen, Shichen; Chen, Jialin; Yun, Dong-Hyun; O'Brien Cox, Anderson; Furdui, Cristina M; Hurley, Edward; Feltri, Maria Laura; Qu, Jun; Hollis, Thomas; Kengne, Jules Berlin Nde; Fongang, Bernard; Sousa, Rui J; Kandel, Mikhail E; Kandel, Eugene S; Hahn, Klaus M; Nikiforov, Mikhail A
信号转导
细胞生物学
RAC1
发表日期：2021
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Cell-Based Methods for the Identification of Myc-Inhibitory Small Molecules

基于细胞的方法鉴定Myc抑制性小分子

期刊:Methods in Molecular Biology
影响因子:
doi:10.1007/978-1-0716-1476-1_19
Burkhart, Catherine A; Haber, Michelle; Norris, Murray D; Gudkov, Andrei V; Nikiforov, Mikhail A
细胞生物学
发表日期：2021
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Targeting Multiple Myeloma through the Biology of Long-Lived Plasma Cells

通过长寿命浆细胞生物学靶向治疗多发性骨髓瘤

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers12082117
Utley, Adam; Lipchick, Brittany; Lee, Kelvin P; Nikiforov, Mikhail A
多发性骨髓瘤
细胞生物学
骨髓瘤
发表日期：2020
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The UALE project: a cross-sectional approach for trends in HIV/STI prevalence among key populations attending STI clinics in Guatemala

UALE项目：危地马拉性病诊所就诊重点人群中艾滋病毒/性传播感染流行趋势的横断面研究

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2018-022632
García, Juan Ignacio; Sabidó, Meritxell; Nikiforov, Mikhail; Smith, Adriana; Hernández, Gabriela; Ortiz, Rudy; Ardani, Luis; Cajas, Alba; Camey, Elsy; Torrelles, Jordi B; Wang, Shu-Hua; Campbell, Colin N J; Folch, Cinta; Casabona, Jordi
HIV
炎症/感染
微生物学
发表日期：2018
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