Nikish相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Persistent chromatin loops shape gene expression plasticity upon stimulation and restimulation of human neurons

持续存在的染色质环在人类神经元受到刺激和再次刺激时塑造基因表达可塑性

doi:10.1101/2025.09.30.679661

Waldman, Abraham J; Pham, Kenneth; Titus, Katelyn R; Nikish, Alexandria; Liu, Constin; Ryu, Han-Seul; Muppidi, Srikar S; Chandradoss, Keerthivasan Raanin; Xu, Peibo; Patel, Rohan; Boya, Ravi; Phillips-Cremins, Jennifer E

发表日期：2025

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A multi-looping chromatin signature predicts dysregulated gene expression in neurons with familial Alzheimer's disease mutations

多环染色质特征预测携带家族性阿尔茨海默病突变的神经元中基因表达失调

doi:10.1101/2024.02.27.582395

Chandrashekar, Harshini; Simandi, Zoltan; Choi, Heesun; Ryu, Han-Seul; Waldman, Abraham J; Nikish, Alexandria; Muppidi, Srikar S; Gong, Wanfeng; Paquet, Dominik; Phillips-Cremins, Jennifer E

阿尔茨海默症

发表日期：2024

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Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction

自闭症相关基因 CHD8 的杂合缺失通过基因表达和染色质压缩的广泛变化损害了突触功能

期刊:American Journal of Human Genetics

影响因子:8.1

doi:10.1016/j.ajhg.2023.09.004

Xi Shi, Congyi Lu, Alba Corman, Alexandra Nikish, Yang Zhou, Randy J Platt, Ivan Iossifov, Feng Zhang, Jen Q Pan, Neville E Sanjana

发表日期：2023

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See(quence) and ye shall find: higher-order genome folding in intact single cells

仔细观察，你就会发现：完整单细胞中的高级基因组折叠

期刊:Molecular Cell

影响因子:16.6

doi:10.1016/j.molcel.2021.02.035

Pham, Kenneth; Nikish, Alexandria; Phillips-Cremins, Jennifer E

细胞生物学

发表日期：2021

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Overexpression of NEUROG2 and NEUROG1 in human embryonic stem cells produces a network of excitatory and inhibitory neurons

NEUROG2 和 NEUROG1 在人类胚胎干细胞中的过度表达产生了兴奋性和抑制性神经元网络

期刊:FASEB Journal

影响因子:4.4

doi:10.1096/fj.201801110RR

Congyi Lu, Xi Shi, Andrew Allen, David Baez-Nieto, Alexandria Nikish, Neville E Sanjana, Jen Q Pan

发育与干细胞

发表日期：2019

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