日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data

通过整合克隆生存数据和多层次分子数据对胶质母细胞瘤细胞系的治疗耐药性进行系统体外分析

Leon Emanuel Schnöller, Daniel Piehlmaier, Peter Weber, Nikko Brix, Daniel Felix Fleischmann, Alexander Edward Nieto, Martin Selmansberger, Theresa Heider, Julia Hess, Maximilian Niyazi, Claus Belka, Kirsten Lauber, Kristian Unger #, Michael Orth #

Integrative analysis of therapy resistance and transcriptomic profiling data in glioblastoma cells identifies sensitization vulnerabilities for combined modality radiochemotherapy

对胶质母细胞瘤细胞的治疗耐药性和转录组分析数据的综合分析可确定联合放化疗的致敏脆弱性

Leon Emanuel Schnöller, Valerie Albrecht, Nikko Brix, Alexander Edward Nieto, Daniel Felix Fleischmann, Maximilian Niyazi, Julia Hess, Claus Belka, Kristian Unger, Kirsten Lauber, Michael Orth

Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90

抑制热休克蛋白 90 可增强放射治疗对抗肿瘤免疫机制的启动

Anne Ernst, Roman Hennel, Julia Krombach, Heidi Kapfhammer, Nikko Brix, Gabriele Zuchtriegel, Bernd Uhl, Christoph A Reichel, Benjamin Frey, Udo S Gaipl, Nicolas Winssinger, Senji Shirasawa, Takehiko Sasazuki, Markus Sperandio, Claus Belka, Kirsten Lauber

The clonogenic assay: robustness of plating efficiency-based analysis is strongly compromised by cellular cooperation

克隆形成试验:基于接种效率的分析的稳健性受到细胞合作的严重损害

Nikko Brix, Daniel Samaga, Roman Hennel, Katharina Gehr, Horst Zitzelsberger, Kirsten Lauber

Priming anti-tumor immunity by radiotherapy: Dying tumor cell-derived DAMPs trigger endothelial cell activation and recruitment of myeloid cells

通过放射疗法引发抗肿瘤免疫:垂死肿瘤细胞衍生的 DAMP 触发内皮细胞活化和髓系细胞募集

Julia Krombach, Roman Hennel, Nikko Brix, Michael Orth, Ulrike Schoetz, Anne Ernst, Jessica Schuster, Gabriele Zuchtriegel, Christoph A Reichel, Susanne Bierschenk, Markus Sperandio, Thomas Vogl, Steffen Unkel, Claus Belka, Kirsten Lauber

A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer

一种新型的 HSP90 抑制剂具有较低的肝毒性,可与放射疗法协同作用,诱导细胞凋亡、消除克隆存活,并改善结直肠癌模型中的肿瘤控制

Linda Kinzel, Anne Ernst, Michael Orth, Valerie Albrecht, Roman Hennel, Nikko Brix, Benjamin Frey, Udo S Gaipl, Gabriele Zuchtriegel, Christoph A Reichel, Andreas Blutke, Daniela Schilling, Gabriele Multhoff, Minglun Li, Maximilian Niyazi, Anna A Friedl, Nicolas Winssinger, Claus Belka, Kirsten Laub

Release of monocyte migration signals by breast cancer cell lines after ablative and fractionated γ-irradiation

乳腺癌细胞系在消融和分次γ射线照射后释放单核细胞迁移信号

Roman Hennel, Nikko Brix, Karin Seidl, Anne Ernst, Heike Scheithauer, Claus Belka, Kirsten Lauber