日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PIEZO mechanosensitivity in chondrocytes is differentially modulated by L-type and T-type voltage-sensitive ion channels

软骨细胞中的压电机械敏感性受L型和T型电压门控离子通道的差异性调节。

Savadipour, Alireza; Marushack, Gabrielle K; Nims, Robert J; Garcia-Castorena, Jaquelin M; Liedtke, Wolfgang; Guilak, Farshid

Activation of the mechanosensitive ion channels TRPV4 and PIEZO1 downregulates key regulatory systems in the chondrocyte mechanome.

机械敏感离子通道 TRPV4 和 PIEZO1 的激活会下调软骨细胞机械组中的关键调节系统

Palmer Daniel R, Nims Robert, Zhang Bo, Guilak Farshid

Mechanogenetics: harnessing mechanobiology for cellular engineering

机械遗传学:利用机械生物学进行细胞工程

Nims, Robert J; Pferdehirt, Lara; Guilak, Farshid

Regulation of chondrocyte biosynthetic activity by dynamic hydrostatic pressure: the role of TRP channels

动态静水压对软骨细胞生物合成活性的调控:TRP通道的作用

Savadipour, Alireza; Nims, Robert J; Katz, Dakota B; Guilak, Farshid

A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues.

用于在工程组织中自主输送药物的合成机械遗传基因回路

Nims Robert J, Pferdehirt Lara, Ho Noelani B, Savadipour Alireza, Lorentz Jeremiah, Sohi Sima, Kassab Jordan, Ross Alison K, O'Conor Christopher J, Liedtke Wolfgang B, Zhang Bo, McNulty Amy L, Guilak Farshid

Immunoengineering the next generation of arthritis therapies

免疫工程打造下一代关节炎疗法

Klimak, Molly; Nims, Robert J; Pferdehirt, Lara; Collins, Kelsey H; Harasymowicz, Natalia S; Oswald, Sara J; Setton, Lori A; Guilak, Farshid

Immature bovine cartilage wear by fatigue failure and delamination

未成熟牛软骨因疲劳失效和分层而磨损

Durney, Krista M; Shaeffer, Courtney A; Zimmerman, Brandon K; Nims, Robert J; Oungoulian, Sevan; Jones, Brian K; Boorman-Padgett, James F; Suh, Jason T; Shah, Roshan P; Hung, Clark T; Ateshian, Gerard A

Designer Stem Cells: Genome Engineering and the Next Generation of Cell-Based Therapies

定制干细胞:基因组工程与下一代细胞疗法

Guilak, Farshid; Pferdehirt, Lara; Ross, Alison K; Choi, Yun-Rak; Collins, KelseyH; Nims, Robert J; Katz, Dakota B; Klimak, Molly; Tabbaa, Suzanne; Pham, Christine T N

Osteoarthritis as a disease of the cartilage pericellular matrix

骨关节炎是一种软骨周围细胞基质疾病

Guilak, Farshid; Nims, Robert J; Dicks, Amanda; Wu, Chia-Lung; Meulenbelt, Ingrid

(*) Constrained Cage Culture Improves Engineered Cartilage Functional Properties by Enhancing Collagen Network Stability.

(*)受限笼培养通过增强胶原蛋白网络稳定性来改善工程软骨的功能特性

Nims Robert J, Cigan Alexander D, Durney Krista M, Jones Brian K, O'Neill John D, Law Wing-Sum A, Vunjak-Novakovic Gordana, Hung Clark T, Ateshian Gerard A