Nina Graffmann相关文献与解析，生知库 | 链接生命科学的每一步

The Nephrotoxin Puromycin Aminonucleoside Induces Injury in Kidney Organoids Differentiated from Induced Pluripotent Stem Cells

肾毒素嘌呤霉素氨基核苷诱导诱导性多能干细胞分化的肾脏类器官损伤

期刊:Cells

影响因子:5.1

doi:10.3390/cells11040635

Lisa Nguyen, Wasco Wruck, Lars Erichsen, Nina Graffmann, James Adjaye

A stem cell based in vitro model of NAFLD enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference

基于干细胞的 NAFLD 体外模型能够分析患者对高脂肪饮食和 AdipoRon 干扰的个体代谢适应情况

期刊:Biology Open

影响因子:1.8

doi:10.1242/bio.054189

Nina Graffmann, Audrey Ncube, Soraia Martins, Aurelian Robert Fiszl, Philipp Reuther, Martina Bohndorf, Wasco Wruck, Mathias Beller, Constantin Czekelius, James Adjaye

The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor Cells

FGF、TGFβ 和 WNT 轴调节人 SIX2+ 尿源性肾脏祖细胞的自我更新

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-020-57723-2

Md Shaifur Rahman # ，Wasco Wruck # ，Lucas-Sebastian Spitzhorn ，Lisa Nguyen ，Martina Bohndorf ，Soraia Martins ，Fatima Asar ，Audrey Ncube ，Lars Erichsen ，Nina Graffmann ，James Adjaye

The presence of human mesenchymal stem cells of renal origin in amniotic fluid increases with gestational time

羊水中肾源性人类间充质干细胞的存在随着妊娠时间的延长而增加

期刊:Stem Cell Research

影响因子:7.1

doi:10.1186/s13287-018-0864-7

Md Shaifur Rahman, Lucas-Sebastian Spitzhorn, Wasco Wruck, Carsten Hagenbeck, Percy Balan, Nina Graffmann, Martina Bohndorf, Audrey Ncube, Pascale V Guillot, Tanja Fehm, James Adjaye

Cell fate decisions of human iPSC-derived bipotential hepatoblasts depend on cell density

人类 iPSC 衍生的双潜能肝母细胞的细胞命运决定取决于细胞密度

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0200416

Nina Graffmann, Audrey Ncube, Wasco Wruck, James Adjaye

Transplanted Human Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Support Liver Regeneration in Gunn Rats

移植人类多能干细胞衍生的间充质干细胞支持 Gunn 大鼠的肝脏再生

期刊:Stem Cells and Development

影响因子:2.5

doi:10.1089/scd.2018.0010

Lucas-Sebastian Spitzhorn, Claus Kordes, Matthias Megges, Iris Sawitza, Silke Götze, Doreen Reichert, Peggy Schulze-Matz, Nina Graffmann, Martina Bohndorf, Wasco Wruck, Jan Philipp Köhler, Diran Herebian, Ertan Mayatepek, Richard O C Oreffo, Dieter Häussinger, James Adjaye

Lymphoblast-derived integration-free iPSC line AD-TREM2-3 from a 74 year-old Alzheimer's disease patient expressing the TREM2 p.R47H variant

来自一名 74 岁阿尔茨海默病患者的淋巴母细胞衍生的无整合 iPSC 系 AD-TREM2-3，表达 TREM2 p.R47H 变体

期刊:Stem Cell Research

影响因子:0.8

doi:10.1016/j.scr.2018.05.018

Soraia Martins, Hatice Yigit, Martina Bohndorf, Nina Graffmann, Aurelian Robert Fiszl, Wasco Wruck, Kristel Sleegers, Christine Van Broeckhoven, James Adjaye

Lymphoblast-derived integration-free iPSC line AD-TREM2-1 from a 67year-old Alzheimer's disease patient expressing the TREM2 p.R47H variant

来自一名 67 岁阿尔茨海默病患者的淋巴母细胞衍生的无整合 iPSC 系 AD-TREM2-1，表达 TREM2 p.R47H 变体

期刊:Stem Cell Research

影响因子:0.8

doi:10.1016/j.scr.2018.03.011

Soraia Martins, Hatice Yigit, Martina Bohndorf, Nina Graffmann, Aurelian Robert Fiszl, Wasco Wruck, Kristel Sleegers, Christine Van Broeckhoven, James Adjaye

Modeling Nonalcoholic Fatty Liver Disease with Human Pluripotent Stem Cell-Derived Immature Hepatocyte-Like Cells Reveals Activation of PLIN2 and Confirms Regulatory Functions of Peroxisome Proliferator-Activated Receptor Alpha

利用人类多能干细胞衍生的未成熟肝细胞样细胞对非酒精性脂肪性肝病进行建模，揭示了 PLIN2 的激活并证实了过氧化物酶体增殖激活受体 α 的调节功能

期刊:Stem Cells and Development

影响因子:2.5

doi:10.1089/scd.2015.0383

Nina Graffmann, Sarah Ring, Marie-Ann Kawala, Wasco Wruck, Audrey Ncube, Hans-Ingo Trompeter, James Adjaye

Forskolin induces FXR expression and enhances maturation of iPSC-derived hepatocyte-like cells

福斯可林诱导 FXR 表达并促进 iPSC 衍生的肝细胞样细胞的成熟

The Nephrotoxin Puromycin Aminonucleoside Induces Injury in Kidney Organoids Differentiated from Induced Pluripotent Stem Cells

肾毒素嘌呤霉素氨基核苷诱导诱导性多能干细胞分化的肾脏类器官损伤

A stem cell based in vitro model of NAFLD enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference

基于干细胞的 NAFLD 体外模型能够分析患者对高脂肪饮食和 AdipoRon 干扰的个体代谢适应情况

The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor Cells

FGF、TGFβ 和 WNT 轴调节人 SIX2+ 尿源性肾脏祖细胞的自我更新

The presence of human mesenchymal stem cells of renal origin in amniotic fluid increases with gestational time

羊水中肾源性人类间充质干细胞的存在随着妊娠时间的延长而增加

Cell fate decisions of human iPSC-derived bipotential hepatoblasts depend on cell density

人类 iPSC 衍生的双潜能肝母细胞的细胞命运决定取决于细胞密度

Transplanted Human Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Support Liver Regeneration in Gunn Rats

移植人类多能干细胞衍生的间充质干细胞支持 Gunn 大鼠的肝脏再生

Lymphoblast-derived integration-free iPSC line AD-TREM2-3 from a 74 year-old Alzheimer's disease patient expressing the TREM2 p.R47H variant

来自一名 74 岁阿尔茨海默病患者的淋巴母细胞衍生的无整合 iPSC 系 AD-TREM2-3，表达 TREM2 p.R47H 变体

Lymphoblast-derived integration-free iPSC line AD-TREM2-1 from a 67year-old Alzheimer's disease patient expressing the TREM2 p.R47H variant

来自一名 67 岁阿尔茨海默病患者的淋巴母细胞衍生的无整合 iPSC 系 AD-TREM2-1，表达 TREM2 p.R47H 变体

Modeling Nonalcoholic Fatty Liver Disease with Human Pluripotent Stem Cell-Derived Immature Hepatocyte-Like Cells Reveals Activation of PLIN2 and Confirms Regulatory Functions of Peroxisome Proliferator-Activated Receptor Alpha

利用人类多能干细胞衍生的未成熟肝细胞样细胞对非酒精性脂肪性肝病进行建模，揭示了 PLIN2 的激活并证实了过氧化物酶体增殖激活受体 α 的调节功能