日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of vascular endothelial growth factor A (VEGFA) isoforms in granulosa cells using pDmrt-1-Cre or Amhr2-Cre reduces fertility by arresting follicular development and by reducing litter size in female mice

使用 pDmrt-1-Cre 或 Amhr2-Cre 导致颗粒细胞中血管内皮生长因子 A (VEGFA) 同工酶的缺失,会通过阻止卵泡发育和减少雌性小鼠的产仔数量来降低生育能力

Kevin M Sargent, Ningxia Lu, Debra T Clopton, William E Pohlmeier, Vanessa M Brauer, Napoleone Ferrara, David W Silversides, Andrea S Cupp

Loss of vascular endothelial growth factor A (VEGFA) isoforms in the testes of male mice causes subfertility, reduces sperm numbers, and alters expression of genes that regulate undifferentiated spermatogonia

雄性小鼠睾丸中血管内皮生长因子 A (VEGFA) 同工酶的缺失会导致生育能力低下、精子数量减少,并改变调节未分化精原细胞的基因表达

Ningxia Lu, Kevin M Sargent, Debra T Clopton, William E Pohlmeier, Vanessa M Brauer, Renee M McFee, John S Weber, Napoleone Ferrara, David W Silversides, Andrea S Cupp

KDR-LacZ-expressing cells are involved in ovarian and testis-specific vascular development, suggesting a role for VEGFA in the regulation of this vasculature

KDR-LacZ 表达细胞参与卵巢和睾丸特异性血管发育,表明 VEGFA 在调节此类血管中发挥作用

Rebecca C Bott, Debra T Clopton, Anna M Fuller, Ryann M McFee, Ningxia Lu, Renee M McFee, Andrea S Cupp