日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Latent-TGF-β has a domain swapped architecture

潜伏型TGF-β具有结构域交换结构

Jin, Mingliang; Seed, Robert I; Shing, Tiffany; Wang, Li; Li, Junrui; Cheng, Yifan; Nishimura, Stephen L

Cryo-EM structure of the αvβ8 integrin reveals a mechanism for stabilizing integrin extension

αvβ8整合素的冷冻电镜结构揭示了一种稳定整合素延伸的机制

Cormier, Anthony; Campbell, Melody G; Ito, Saburo; Wu, Shenping; Lou, Jianlong; Marks, James; Baron, Jody L; Nishimura, Stephen L; Cheng, Yifan

Integrin αvβ8-expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells.

表达整合素αvβ8的肿瘤细胞通过调节免疫细胞中的TGF-β活化来逃避宿主免疫

Takasaka Naoki, Seed Robert I, Cormier Anthony, Bondesson Andrew J, Lou Jianlong, Elattma Ahmed, Ito Saburo, Yanagisawa Haruhiko, Hashimoto Mitsuo, Ma Royce, Levine Michelle D, Publicover Jean, Potts Rashaun, Jespersen Jillian M, Campbell Melody G, Conrad Fraser, Marks James D, Cheng Yifan, Baron Jody L, Nishimura Stephen L

Cigarette smoke exposure worsens acute lung injury in antibiotic-treated bacterial pneumonia in mice.

在接受抗生素治疗的细菌性肺炎小鼠模型中,吸烟会加重急性肺损伤

Gotts Jeffrey E, Chun Lauren, Abbott Jason, Fang Xiaohui, Takasaka Naoki, Nishimura Stephen L, Springer Matthew L, Schick Suzaynn F, Calfee Carolyn S, Matthay Michael A

Cigarette Smoke Exposure Worsens Endotoxin-Induced Lung Injury and Pulmonary Edema in Mice

香烟烟雾暴露会加重小鼠内毒素诱导的肺损伤和肺水肿

Gotts, Jeffrey E; Abbott, Jason; Fang, Xiaohui; Yanagisawa, Haru; Takasaka, Naoki; Nishimura, Stephen L; Calfee, Carolyn S; Matthay, Michael A

Liver capsule: Age-influenced hepatic immune priming determines HBV infection fate: Implications from mouse to man

肝包膜:年龄影响的肝脏免疫启动决定乙肝病毒感染的命运:从小鼠到人类的启示

Publicover, Jean; Jespersen, Jillian M; Johnson, Audra J; Nishimura, Stephen L; Goodsell, Amanda; Wakil, Adil E; Rosenthal, Philip; Pai, Eric; Avanesyan, Lia; Cooper, Stewart; Baron, Jody L

A critical role for dendritic cells in the evolution of IL-1β-mediated murine airway disease

树突状细胞在IL-1β介导的小鼠气道疾病发展过程中发挥关键作用

Hashimoto, Mitsuo; Yanagisawa, Haruhiko; Minagawa, Shunsuke; Sen, Debasish; Goodsell, Amanda; Ma, Royce; Moermans, Catherine; McKnelly, Kate J; Baron, Jody L; Krummel, Matthew F; Nishimura, Stephen L

TGF-β-Dependent Dendritic Cell Chemokinesis in Murine Models of Airway Disease

气道疾病小鼠模型中TGF-β依赖性树突状细胞趋化运动

Hashimoto, Mitsuo; Yanagisawa, Haruhiko; Minagawa, Shunsuke; Sen, Debasish; Ma, Royce; Murray, Lynne A; Tsui, Ping; Lou, Jianlong; Marks, James D; Baron, Jody L; Krummel, Matthew F; Nishimura, Stephen L

Selective targeting of TGF-β activation to treat fibroinflammatory airway disease

选择性靶向TGF-β激活治疗纤维炎症性气道疾病

Minagawa, Shunsuke; Lou, Jianlong; Seed, Robert I; Cormier, Anthony; Wu, Shenping; Cheng, Yifan; Murray, Lynne; Tsui, Ping; Connor, Jane; Herbst, Ronald; Govaerts, Cedric; Barker, Tyren; Cambier, Stephanie; Yanagisawa, Haruhiko; Goodsell, Amanda; Hashimoto, Mitsuo; Brand, Oliver J; Cheng, Ran; Ma, Royce; McKnelly, Kate J; Wen, Weihua; Hill, Arthur; Jablons, David; Wolters, Paul; Kitamura, Hideya; Araya, Jun; Barczak, Andrea J; Erle, David J; Reichardt, Louis F; Marks, James D; Baron, Jody L; Nishimura, Stephen L

Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells.

IPF 中上皮细胞衰老加速以及 SIRT6 在 TGF-β 诱导的人类支气管上皮细胞衰老中的抑制作用

Minagawa Shunsuke, Araya Jun, Numata Takanori, Nojiri Satoko, Hara Hiromichi, Yumino Yoko, Kawaishi Makoto, Odaka Makoto, Morikawa Toshiaki, Nishimura Stephen L, Nakayama Katsutoshi, Kuwano Kazuyoshi