Co-inhibition of Notch1 and ChK1 triggers genomic instability and melanoma cell death increasing the lifespan of mice bearing melanoma brain metastasis.
Notch1 和 ChK1 的共同抑制可引发基因组不稳定和黑色素瘤细胞死亡，从而延长患有黑色素瘤脑转移的小鼠的寿命
期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-025-03411-w
Thakur Varsha, Thakur Vijay S, Wang Dazhi, de Freitas Juliano Tiburcio, Bianchi Anna, Nivelo Luis Alberto, Umland Oliver, Welford Scott M, Bedogni Barbara
