日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Drug repurposing for Alzheimer's disease: a Delphi consensus and stakeholder consultation

阿尔茨海默病药物再利用:德尔菲共识和利益相关者咨询

Corbett, Anne; Sultana, Janet; Stych, Kate; Mills, Roger; Cummings, Jeff L; Williams, Gareth; Ismail, Zahinoor; Soto-Martin, Maria; Mintzer, Jacobo; Gauthier, Serge; Greig, Nigel H; Noble, Wendy; Killick, Richard; Lai, Mitchell K P; Routledge, Carol; Walsh, Frank; Fillit, Howard; Aarsland, Dag; Lane, Roger; Mills, Kathryn; Ballard, Clive

Alzheimer's disease brain-derived tau extracts show differential processing and transcriptional effects in human astrocytes.

阿尔茨海默病脑源性 tau 蛋白提取物在人类星形胶质细胞中表现出不同的加工和转录效应

Reid Matthew J, Salazar Melissa Leija, Troakes Claire, Lynham Steven, Srivastava Deepak P, Perez-Nievas Beatriz Gomez, Noble Wendy

Truncated tau disrupts autophagy and endolysosomal systems

截短的tau蛋白会破坏自噬和内溶酶体系统。

Pollack, Saskia J; Hanger, Diane P; Noble, Wendy; Jimenez-Sanchez, Maria

Astrocyte adaptation in Alzheimer's disease: a focus on astrocytic P2X7R

阿尔茨海默病中星形胶质细胞的适应性变化:聚焦于星形胶质细胞P2X7R受体

Beltran-Lobo, Paula; Reid, Matthew J; Jimenez-Sanchez, Maria; Verkhratsky, Alexei; Perez-Nievas, Beatriz G; Noble, Wendy

Targeting ER-Mitochondria Signaling as a Therapeutic Target for Frontotemporal Dementia and Related Amyotrophic Lateral Sclerosis

以内质网-线粒体信号通路为靶点治疗额颞叶痴呆及相关肌萎缩侧索硬化症

Martín-Guerrero, Sandra M; Markovinovic, Andrea; Mórotz, Gábor M; Salam, Shaakir; Noble, Wendy; Miller, Christopher C J

The PTPIP51 coiled-coil domain is important in VAPB binding, formation of ER-mitochondria contacts and IP3 receptor delivery of Ca(2+) to mitochondria

PTPIP51卷曲螺旋结构域在VAPB结合、内质网-线粒体接触的形成以及IP3受体向线粒体递送Ca(2+)方面发挥重要作用。

Mórotz, Gábor M; Martín-Guerrero, Sandra M; Markovinovic, Andrea; Paillusson, Sebastien; Russell, Matthew R G; Machado, Pedro M Pereira; Fleck, Roland A; Noble, Wendy; Miller, Christopher C J

A Thalamic Orphan Receptor Drives Variability in Short-Term Memory

丘脑孤儿受体驱动短期记忆的变化

Kuangfu Hsiao, Chelsea Noble, Wendy Pitman, Nakul Yadav, Suraj Kumar, Gregory R Keele, Andrea Terceros, Matt Kanke, Tara Conniff, Christopher Cheleuitte-Nieves, Ravi Tolwani, Praveen Sethupathy, Priyamvada Rajasethupathy

Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A Randomized Clinical Trial

米诺环素两种不同剂量与安慰剂治疗轻度阿尔茨海默病患者的随机临床试验

Howard, Robert; Zubko, Olga; Bradley, Rosie; Harper, Emma; Pank, Lynn; O'Brien, John; Fox, Chris; Tabet, Naji; Livingston, Gill; Bentham, Peter; McShane, Rupert; Burns, Alistair; Ritchie, Craig; Reeves, Suzanne; Lovestone, Simon; Ballard, Clive; Noble, Wendy; Nilforooshan, Ramin; Wilcock, Gordon; Gray, Richard

Astrocytes in Tauopathies

Tau蛋白病中的星形胶质细胞

Reid, Matthew J; Beltran-Lobo, Paula; Johnson, Louisa; Perez-Nievas, Beatriz Gomez; Noble, Wendy

Enteric synucleinopathy: from trendy concept to real entity

肠道突触核蛋白病:从时髦概念到真实存在的疾病

de Guilhem de Lataillade, Adrien; Lebouvier, Thibaud; Noble, Wendy; Leclair-Visonneau, Laurène; Derkinderen, Pascal