日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Modulation of neutrophil-to-lymphocyte ratio and gut microbiome balance in astronauts: potential benefits of novel beta-glucans during space missions

调节宇航员中性粒细胞与淋巴细胞比例和肠道微生物群平衡：新型β-葡聚糖在太空任务中的潜在益处

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1538147
Ikewaki, Nobunao; Ichiyama, Koji; Senthilkumar, Rajappa; Preethy, Senthilkumar; Abraham, Samuel J K
微生物学
细胞生物学
中性粒细胞
粒细胞
发表日期：2025
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Enhanced expression of dystrophin, IGF-1, CD44 and MYH3 in plasma and skeletal muscles including diaphragm of mdx mice after oral administration of Neu REFIX beta 1,3-1,6 glucan.

口服 Neu REFIX β 1,3-1,6 葡聚糖后，mdx 小鼠血浆和骨骼肌（包括膈肌）中肌营养不良蛋白、IGF-1、CD44 和 MYH3 的表达增强

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-92258-4
Preethy Senthilkumar, Sakamoto Shuji, Higuchi Takuma, Ichiyama Koji, Yamamoto Naoki, Ikewaki Nobunao, Iwasaki Masaru, Dedeepiya Vidyasagar Devaprasad, Srinivasan Subramaniam, Raghavan Kadalraja, Rajmohan Mathaiyan, Senthilkumar Rajappa, Abraham Samuel Jk
骨科研究
CD44
IGF-1
T细胞
发表日期：2025
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Improving the therapeutic efficacy of gene therapy for duchenne muscular dystrophy (DMD) by evaluating and managing inflammation

通过评估和管理炎症来提高杜氏肌营养不良症 (DMD) 基因疗法的治疗效果

期刊:Frontiers in Genetics
影响因子:2.8
doi:10.3389/fgene.2025.1569289
Raghavan, Kadalraja; Ikewaki, Nobunao; Preethy, Senthilkumar; Abraham, Samuel J K
炎症/感染
炎症
DMD
发表日期：2025
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Randomised trial of Aureobasidium pullulans-produced beta 1,3-1,6-glucans in patients with Duchenne muscular dystrophy: favourable changes in gut microbiota and clinical outcomes indicating their potential in epigenetic manipulation

一项针对杜氏肌营养不良症患者的随机试验表明，由出芽短梗霉产生的β-1,3-1,6-葡聚糖可改善肠道菌群并改善临床疗效，提示其在表观遗传调控方面具有潜在应用价值。

期刊:BMJ Nutrition, Prevention and Health
影响因子:2.5
doi:10.1136/bmjnph-2023-000776
Raghavan, Kadalraja; Dedeepiya, Vidyasagar Devaprasad; Yamamoto, Naoki; Ikewaki, Nobunao; Iwasaki, Masaru; Dinassing, Ashwamed; Senthilkumar, Rajappa; Preethy, Senthilkumar; Abraham, Samuel J K
微生物学
信号转导
肠道菌群
表观遗传
发表日期：2025
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Commentary: The ME-BYO index: A development and validation project of a novel comprehensive health index

评论：ME-BYO 指数：一项新型综合健康指数的开发和验证项目

期刊:Frontiers in Public Health
影响因子:3.4
doi:10.3389/fpubh.2024.1495056
Ikewaki, Nobunao; Ichiyama, Koji; Senthilkumar, Rajappa; Preethy, Senthilkumar; Abraham, Samuel J K
发表日期：2024
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Dual Deletion of Keap1 and Rbpjκ Genes in Liver Leads to Hepatomegaly and Hypercholesterolemia

肝脏中 Keap1 和 Rbpjκ 基因双重缺失导致肝肿大和高胆固醇血症

期刊:International Journal of Molecular Sciences
影响因子:0.7
doi:10.3390/ijms25094712
Nobunao Wakabayashi, Yoko Yagishita, Tanvi Joshi, Thomas W Kensler
代谢
发表日期：2024
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Transcriptional Regulation of Math1 by Aryl Hydrocarbon Receptor: Effect on Math1+ Progenitor Cells in Mouse Small Intestine

芳基烃受体对 Math1 的转录调控：对小鼠小肠 Math1+ 祖细胞的影响

期刊:Molecular and Cellular Biology
影响因子:3.2
doi:10.1080/10985549.2022.2160610
Yoko Yagishita, Tanvi Joshi, Thomas W Kensler, Nobunao Wakabayashi
细胞生物学
其它细胞
Mouse
发表日期：2023
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Benefits of Gut Microbiota Reconstitution by Beta 1,3-1,6 Glucans in Subjects with Autism Spectrum Disorder and Other Neurodegenerative Diseases

β-1,3-1,6葡聚糖对自闭症谱系障碍和其他神经退行性疾病患者肠道菌群重建的益处

期刊:Journal of Alzheimers Disease
影响因子:3.1
doi:10.3233/JAD-220388
Raghavan, Kadalraja; Dedeepiya, Vidyasagar Devaprasad; Yamamoto, Naoki; Ikewaki, Nobunao; Sonoda, Tohru; Iwasaki, Masaru; Kandaswamy, Ramesh Shankar; Senthilkumar, Rajappa; Preethy, Senthilkumar; Abraham, Samuel J K
微生物学
肠道菌群
自闭症
神经科学
发表日期：2023
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Beneficial immune-modulatory effects of the N-163 strain of Aureobasidium pullulans-produced 1,3-1,6 Beta glucans in Duchenne muscular dystrophy: Results of an open-label, prospective, exploratory case-control clinical study

出芽短梗霉 N-163 菌株产生的 1,3-1,6 β-葡聚糖对杜氏肌营养不良症的有益免疫调节作用：一项开放性、前瞻性、探索性病例对照临床研究的结果

期刊:IBRO Neuroscience Reports
影响因子:2
doi:10.1016/j.ibneur.2023.06.007
Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Subramaniam Srinivasan, Subramanian Pushkala, Sudhakar S Bharatidasan, Nobunao Ikewaki, Masaru Iwasaki, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel J K Abraham2
免疫
发表日期：2023
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Beneficial effects of 1,3-1,6 β-glucans produced by Aureobasidium pullulans on non-esterified fatty acid levels in diabetic KKAy mice and their potential implications in metabolic dysregulation

由出芽短梗霉产生的1,3-1,6 β-葡聚糖对糖尿病KKAy小鼠非酯化脂肪酸水平的有益作用及其在代谢紊乱中的潜在意义

期刊:Journal of Diabetes and Metabolic Disorders
影响因子:1.6
doi:10.1007/s40200-022-01170-5
Ikewaki, Nobunao; Ikeue, Yasunori; Nagataki, Mitsuru; Kurosawa, Gene; Dedeepiya, Vidyasagar Devaprasad; Rajmohan, Mathaiyan; Vaddi, Suryaprakash; Senthilkumar, Rajappa; Preethy, Senthilkumar; Abraham, Samuel J K
糖尿病
代谢
发表日期：2023
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