Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial
RNA干扰药物对健康志愿者体内前蛋白转化酶枯草杆菌蛋白酶/kexin 9型（PCSK9）合成及血清低密度脂蛋白胆固醇浓度的影响：一项随机、单盲、安慰剂对照的I期试验
期刊:Lancet
影响因子:88.5
doi:10.1016/S0140-6736(13)61914-5
Fitzgerald, Kevin; Frank-Kamenetsky, Maria; Shulga-Morskaya, Svetlana; Liebow, Abigail; Bettencourt, Brian R; Sutherland, Jessica E; Hutabarat, Renta M; Clausen, Valerie A; Karsten, Verena; Cehelsky, Jeffrey; Nochur, Saraswathy V; Kotelianski, Victor; Horton, Jay; Mant, Timothy; Chiesa, Joseph; Ritter, James; Munisamy, Malathy; Vaishnaw, Akshay K; Gollob, Jared A; Simon, Amy
