日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of an ITK and TRK kinase inhibitor for the potential topical treatment of atopic dermatitis

发现一种ITK和TRK激酶抑制剂,可用于治疗特应性皮炎。

Duffen, Jennifer L; Crouse, Kimberly K; Ji, Lin; Brault, Amy L; Ford, Kristen; Brooks, Jonathan; Jelinsky, Scott A; Li, Yizheng; Shin, Julia H; Zhao, Yajuan; Andreyeva, Tatyana; Hammerman, Katherine; Arnold, Christina; Sheldon, Richard T; Garren, Jeonifer; LaBarge, Wes; Resek, Anthony; Volmer, Jon; Bagley, Scott W; Casimiro-Garcia, Agustin; Chinigo, Gary M; Davoren, Jennifer E; Denny, Rajiah Aldrin; Drozda, Susan; Foley, Timothy L; Hicklin, Robert W; Liu, Shenping; Lovering, Frank E; Nedoma, Nicole L; Parikh, Mihir D; Strohbach, Joseph W; Trujillo, John I; Steyn, Stefanus J; Nocka, Karl; Hegen, Martin; Vincent, Fabien; Lee, Katherine L; Gerstenberger, Brian S; Primiano, Michael J

"Design principles of a membrane-spanning ubiquitin ligase"

“跨膜泛素连接酶的设计原则”

Williams, Carys; Nocka, Laura M; Hedger, George; Parashara, Pragya; Pardon, Els; Latorraca, Naomi R; Pusapati, Ganesh V; Lartey, Dorothy; Gao, Lei; Milenkovic, Ljiljana; Chalk, Rod; Steyaert, Jan; Marqusee, Susan; Carrique, Loïc; Bazan, J Fernando; Rouse, Sarah L; Kong, Jennifer H; Siebold, Christian; Rohatgi, Rajat

Stimulation of the catalytic activity of the tyrosine kinase Btk by the adaptor protein Grb2

衔接蛋白 Grb2 刺激酪氨酸激酶 Btk 的催化活性

Laura M Nocka, Timothy J Eisen, Anthony T Iavarone, Jay T Groves, John Kuriyan

A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane

EGFR胞质尾和Grb2的双组分蛋白凝聚体通过膜上的SOS信号通路调节Ras的激活。

Lin, Chun-Wei; Nocka, Laura M; Stinger, Brittany L; DeGrandchamp, Joseph B; Lew, L J Nugent; Alvarez, Steven; Phan, Henry T; Kondo, Yasushi; Kuriyan, John; Groves, Jay T

A saturation-mutagenesis analysis of the interplay between stability and activation in Ras

Ras 稳定性与活化作用相互作用的饱和诱变分析

Frank Hidalgo #, Laura M Nocka #, Neel H Shah, Kent Gorday, Naomi R Latorraca, Pradeep Bandaru, Sage Templeton, David Lee, Deepti Karandur, Jeffrey G Pelton, Susan Marqusee, David Wemmer, John Kuriyan

Paying for PrEP: A qualitative study of cost factors that impact pre-exposure prophylaxis uptake in the US

支付暴露前预防费用:一项关于影响美国暴露前预防接受度的成本因素的定性研究

Sosnowy, Collette; Predmore, Zachary; Dean, Lorraine T; Raifman, Julia; Chu, Christina; Galipeau, Drew; Nocka, Kristen; Napoleon, Siena; Chan, Philip

Discovery and multi-parametric optimization of a high-affinity antibody against interleukin-25 with neutralizing activity in a mouse model of skin inflammation

在小鼠皮肤炎症模型中发现并多参数优化具有中和活性的抗白细胞介素-25 高亲和力抗体

Ruth Bone, Brian J Fennell, Amy Tam, Richard Sheldon, Karl Nocka, Sreeja Varghese, Chew Shun Chang, Heike C Hawerkamp, Aoife Yeow, Sean P Saunders, Emily Hams, Patrick T Walsh, Orla Cunningham, Padraic G Fallon

Primary Care for Transgender Adolescents and Young Adults in Rhode Island: An Analysis of the all Payers Claims Database

罗德岛州跨性别青少年和青年人的初级保健:所有支付方索赔数据库分析

Nocka, Kristen; Montgomery, Madeline C; Progovac, Ana; Guss, Carly E; Chan, Philip A; Raifman, Julia

Coupled membrane lipid miscibility and phosphotyrosine-driven protein condensation phase transitions

膜脂互溶性和磷酸酪氨酸驱动的蛋白质凝聚相变之间的耦合

Jean K Chung,William Y C Huang,Catherine B Carbone,Laura M Nocka,Atul N Parikh,Ronald D Vale,Jay T Groves

Evaluating statewide HIV preexposure prophylaxis implementation using All-Payer Claims Data

利用全付费方理赔数据评估全州范围内的艾滋病毒暴露前预防实施情况

Raifman, Julia; Nocka, Kristen; Galárraga, Omar; Wilson, Ira B; Crowley, Christina; Tao, Jun; Napoleon, Siena; Marak, Theodore; Chan, Philip A