A metabolic inhibitor blocks cellular fucosylation and enables production of afucosylated antibodies
代谢抑制剂可阻断细胞岩藻糖基化,从而产生无岩藻糖基化的抗体。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2314026121
Gilormini, Pierre-André; Thota, V Narasimharao; Fers-Lidou, Anthony; Ashmus, Roger A; Nodwell, Matthew; Brockerman, Jacob; Kuo, Chu-Wei; Wang, Yang; Gray, Taylor E; Nitin; McDonagh, Anthony W; Guu, Shih-Yun; Ertunc, Nursah; Yeo, Dominick; Zandberg, Wesley F; Khoo, Kay-Hooi; Britton, Robert; Vocadlo, David J